Boston Heart HDL Map

The amount of apoA-I protein in each of the five HDL subclasses, providing information to accurately identify patients at increased cardiovascular disease risk.

5 Biomarkers Included

α-1 HDL

Very large, mature HDL particles rich in cholesterol, considered the most protective for cardiovascular health.

α-2 HDL

Large HDL particles rich in cholesterol that are cardioprotective but slightly less so than the larger α-1 HDL.

α-3 HDL

Medium-sized HDL particle with intermediate roles in cholesterol transport but unlike the most protective large α-1 HDL, it is less effective at removing cholesterol from arteries and is considered a risk factor.

α-4 HDL

Small HDL particles that have reduced cholesterol-carrying capacity and are less protective.

preβ-1 HDL

Very small, nascent HDL particles that initiate reverse cholesterol transport; high levels may indicate impaired HDL maturation.