The Celiac Disease Panel helps detect an autoimmune reaction triggered by gluten, a protein found in wheat, barley, and rye. In people with celiac disease, the immune system mistakenly attacks the lining of the small intestine when gluten is consumed, leading to inflammation, nutrient malabsorption, and a range of symptoms—from digestive issues to fatigue, joint pain, and skin rashes. This panel includes two important markers: Total IgA, which ensures your immune system is capable of producing antibodies, and Tissue Transglutaminase IgA (tTG-IgA), the most specific antibody linked to celiac disease.
This test is especially useful for diagnosing celiac disease in people with chronic digestive complaints, unexplained nutrient deficiencies (like iron or B12), or autoimmune conditions such as type 1 diabetes or thyroid disease. A positive result doesn’t confirm the diagnosis on its own but strongly suggests that further evaluation, such as an intestinal biopsy or genetic testing, may be needed. Early detection is crucial, as untreated celiac disease can lead to long-term complications like osteoporosis, infertility, or increased cancer risk.
