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The big picture: The Rh factor (Rhesus factor) refers to a protein that may or may not be present on the surface of red blood cells. The presence of this antigen determines whether a person’s blood is classified as Rh-positive (Rh+) or Rh-negative (Rh-).

Rh Positive (Rh+): The Rh antigen is present on the surface of red blood cells. This is the more common type, with around 85% of the population being Rh-positive.

Rh Negative (Rh-): The Rh antigen is absent. Rh-negative individuals can deve