The Thyroid Antibodies Panel helps detect autoimmune thyroid conditions by measuring two specific antibodies: Anti-TPO and Thyroglobulin Antibodies. These are immune system proteins that mistakenly target parts of the thyroid gland. When elevated, they indicate that your body may be attacking its own thyroid tissue, which can gradually impair thyroid function—even if your thyroid hormone levels are still normal.
This test is especially important if you’re experiencing symptoms like fatigue, cold intolerance, weight changes, or brain fog that don’t seem to match your lab results. It’s commonly used to diagnose or confirm Hashimoto’s thyroiditis (the most common cause of hypothyroidism) and Graves’ disease (a common cause of hyperthyroidism). Early detection of these antibodies can help guide more personalized treatment and may explain symptoms that standard thyroid panels can miss.