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This is where the evidence is strongest. A meta-analysis pooling data from 12 randomized controlled trials with over 1,000 adults found that ashwagandha significantly reduced both anxiety and stress levels compared to placebo. The doses that performed best fell in the range of 300 to 600 mg per day of ashwagandha extract.
That's a meaningful finding. Twelve trials and a thousand participants isn't a massive body of evidence, but for a supplement, it's more than most can claim. If stress relief is your main reason for considering ashwagandha, you're looking at the most well-supported use.
A systematic review of five randomized trials involving about 400 people found a small but statistically significant improvement in both sleep quality and how long people slept. Two details stand out:
So if you sleep reasonably well and you're hoping a gummy will turn good sleep into great sleep, the research is less encouraging. But if you genuinely struggle with insomnia and you're willing to stick with it for a couple of months, there may be a modest benefit worth exploring.
One trial tested 225 mg per day of a liposomal form of ashwagandha (a formulation designed for better absorption) in healthy young adults over 30 days. Compared to placebo, participants showed improvements in memory, attention, and reaction time, along with reduced feelings of tension and fatigue.
That's promising, but it's a single study using a specialized formulation. Liposomal delivery is designed to increase how much of the active ingredient your body actually absorbs, so these results may not translate directly to a standard gummy. It's a reason for cautious optimism, not a guarantee.
The research points to a fairly clear range depending on your goal:
If your gummy label lists ashwagandha but doesn't specify the extract amount, or buries it inside a "proprietary blend," you have no way to know if you're getting a dose that matches what's been studied. Many clinical trials used standardized extracts with verified content and contaminant testing, a level of quality control that not every commercial gummy meets.
Most clinical trials report that ashwagandha is well tolerated, even at higher doses, with few serious side effects. A recent narrative review confirmed this generally favorable safety profile.
But "generally safe" isn't the same as "risk-free." There are rare documented cases of drug-induced liver injury linked to ashwagandha supplements. One case specifically involved a man taking ashwagandha gummies twice daily. His liver tests returned to normal after he stopped all supplements, but it's a reminder that "natural" doesn't automatically mean harmless.
The research also flags that we still lack solid long-term safety data and high-dose safety data. Most trials run for a few weeks to a few months. If you're planning to take ashwagandha indefinitely, you're venturing beyond what the current evidence can fully vouch for.
Here's the honest gap in the research: almost no studies have actually used gummy formulations. The active compounds are the same as in capsules and powders, so the benefits should apply if the gummy delivers a comparable dose. But absorption can differ between formats, especially compared to specialized forms like liposomal ashwagandha.
Quality also varies widely between brands. The clinical trials that produced positive results used extracts that were standardized and independently tested. A gummy that tastes like mixed berries and sits on a convenience store shelf may or may not contain what its label promises.
If the research here resonates with your situation, a few practical steps can help you get closer to what the studies actually tested:
People most likely to benefit are those dealing with ongoing stress or insomnia who want a modest, evidence-supported edge. People who should be cautious include anyone with liver disease, anyone taking multiple supplements or medications, anyone who is pregnant, and anyone planning to use ashwagandha long term without medical guidance. For those groups, a conversation with a clinician before starting is worth the effort.