Magnesium Spray Benefits: Here's What the Research Actually Shows

Can Your Skin Actually Absorb Enough Magnesium?

This is the central question, and the research isn't encouraging. A comprehensive 2017 review of transdermal magnesium looked at the available evidence for sprays, oils, and baths and concluded that promoting skin absorption of magnesium is "scientifically unsupported." The same review found no demonstration that transdermal magnesium is superior to simply taking it by mouth.

The claims you see on product labels and wellness blogs, that skin absorption is "better" and causes fewer side effects than oral supplements, are considered marketing rather than evidence-based conclusions.

Has Anyone Tested Magnesium Sprays in People?

Yes, but the studies are small and the results are underwhelming.

The best available trial was a small pilot study of just 25 people who applied a magnesium cream delivering 56 mg per day for two weeks. Compared to placebo, the cream group saw an 8.5% rise in serum magnesium (the placebo group rose 2.6%). That sounds promising until you look closer:

• The difference was only statistically significant in a small subgroup of non-athletes, not in the full study population.
• Changes in 24-hour urinary magnesium, another way to measure whether your body is actually taking in more magnesium, were small and not statistically significant.
• The study lasted just two weeks with only 25 participants, which makes it a preliminary finding at best, not a reliable conclusion.

The other human trial that gets cited involved only nine people using magnesium oil. That study measured magnesium levels in hair, which researchers consider a weak marker, and collected no blood magnesium data at all. Its evidential value is very low.

What About the Benefits People Swear By, Like Better Sleep or Less Anxiety?

This is where the disconnect between marketing and evidence becomes clearest. Magnesium itself does have research supporting benefits for things like blood pressure, mood, pain, and inflammation. But that evidence comes from studies using oral supplements or intravenous magnesium, not from sprays or creams applied to the skin.

No published research has demonstrated that magnesium sprays specifically improve anxiety, sleep, pain, or mood. And no head-to-head trials have compared sprays to oral supplements to see if they perform similarly, worse, or better.

So when a magnesium spray brand references "clinically studied benefits of magnesium," they're borrowing results from an entirely different delivery method. It's a bit like claiming a vitamin C face cream will prevent scurvy because eating oranges does.

Spend Your Money Where the Evidence Points

If you're concerned about your magnesium levels or hoping to get the mood, sleep, or muscle benefits associated with magnesium, the research points clearly in one direction: oral supplementation and dietary intake remain the evidence-based options.

That doesn't mean magnesium sprays are harmful. If you enjoy the ritual or find them soothing, there's no strong reason to stop. But if you're relying on a spray as your primary strategy for correcting a deficiency or managing a health concern, current evidence suggests you're likely not getting what you're paying for. A well-tested oral magnesium supplement, or simply eating more magnesium-rich foods, gives you a much stronger foundation backed by actual clinical data.