2-minute questionnaire
Answer questions about your history, prior treatments, and cardiovascular goals. No appointment needed.
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Repatha (evolocumab) is a PCSK9 inhibitor for serious LDL reduction. Instalab handles physician review and insurance, and keeps your labs on schedule so you actually get it and stay on it.
No appointments. No clinic visits. A licensed physician reviews your case, checks what you'll pay, and, if appropriate, sends the prescription to your pharmacy.
Answer questions about your history, prior treatments, and cardiovascular goals. No appointment needed.
A licensed physician evaluates your eligibility, usually within 1 business day, and reaches out if they need anything else.
We check your options, enroll you in Amgen's patient assistance program, and, if your plan covers Repatha, file the paperwork. You see your exact monthly cost before you commit.
Your Repatha pen is sent to your preferred pharmacy. We'll walk you through self-injection and check in after your first dose.
Two line items: Instalab Membership and the Repatha medication itself. No hidden fees.
Physician oversight and ongoing follow-up
Evolocumab auto-injector, billed by pharmacy
Why pay a membership fee? Repatha needs a physician who actually knows the drug. Membership covers the visits, prescription renewals, and cost paperwork, whether you end up on insurance or the Amgen assistance program. We also recommend a lab recheck around 6 to 8 weeks and follow up on your results, though lab costs are billed separately.
Most commercial plans will, if you have one of: familial hypercholesterolemia, established cardiovascular disease (prior heart attack, stroke, or stented artery), or documented statin intolerance. Medicare Part D typically covers it under the same criteria. We check your plan and file the prior authorization either way. If approval is denied, Amgen's patient assistance program can bring cash cost down to ~$239/mo.
It needs a physician who knows the drug and regular labs to confirm it's doing its job. Here's how our team handles that for you.
A licensed physician reviews your history and labs, confirms Repatha is right for you, and writes the prescription. In parallel, we enroll you in Amgen's patient assistance program and verify your insurance coverage. If you'd rather skip insurance, this takes as little as one day.
Your pen can be picked up at or delivered by your preferred pharmacy. We can walk you through the first injection, and check in the next day.
We recommend rechecking LDL and ApoB at a lab near you, and your physician reviews the results with you. Labs are billed separately. Rechecking is optional, but most patients want to see their numbers move.
Your physician tracks your labs over time and adjusts the plan as your numbers evolve. We keep your prescription and patient assistance enrollment active, so you don't lose a year of progress to paperwork.
Schedule a PCP visit. Wait months. Hope they know the drug. Track down patient assistance yourself. Book and chase your own labs.
2-minute questionnaire. Physician review within 1 business day. Insurance and patient assistance handled. Lab reminders built in.
Repatha comes in a pre-filled auto-injector pen. Press it to your thigh, stomach, or upper arm, hold for about ten seconds, done. Most patients say they barely feel it.
Statins slow cholesterol production in the liver. Repatha takes a different path: it blocks PCSK9, so your liver keeps more LDL receptors active and clears more LDL from your blood. It works on its own or alongside a statin.
Published in NEJM in 2017, FOURIER randomized 27,564 patients with established cardiovascular disease to Repatha or placebo on top of a statin. Over a median 2.2 years, Repatha reduced LDL by a median 59% and cut the composite of cardiovascular death, heart attack, stroke, hospitalization for unstable angina, or coronary revascularization by 15%.
Three patients, 8 to 14 weeks in.
“I was on rosuvastatin for years and still stuck. Repatha finally moved my numbers fast.”
“I kept hearing to wait and recheck. This was the first time treatment actually changed my trajectory.”
“My PCP told me I’d probably be denied and didn’t want to fight it. Instalab got my prior authorization approved in nine days. I’d been putting this off for a year.”
Repatha is a prescription medicine. Important safety information applies. Side effects include injection-site reactions, cold-lile symptoms, and mild muscle aches. Serious side effects are uncommon.
Answer a few questions about your history and goals. A physician reviews your case and, if appropriate, prescribes Repatha. You'll see your exact monthly cost before you start.
Cancel anytime before your first dose.