High Quality Glutamine Supplements

Glutamine is the most abundant amino acid in the body and the primary fuel for intestinal cells and immune cells. It's used for gut lining repair (leaky gut), post-surgical recovery, and supporting immune function during stress.

5 g once or twice daily for general gut and immune support. Higher doses (10–30 g/day) are used in clinical settings for severe gut issues or post-surgical recovery, but should be guided by a clinician.

People with cancer or a history should avoid high-dose glutamine without oncology guidance. People with kidney or liver disease should also consult a clinician. Otherwise, it's well-tolerated.

For gut healing: on an empty stomach (15–30 min before meals) so it reaches the small intestine without competing with other amino acids. For recovery: post-workout. For immune support during stress: any time, with or without food.

Modestly. Glutamine reduces muscle soreness and supports immune function during heavy training, but it doesn't significantly increase muscle protein synthesis like leucine or whey protein. It's more relevant for endurance athletes and those with gut symptoms during high training load.

Limited data. Low-dose dietary intake is fine, but supplemental glutamine isn't well-studied in pregnancy. Talk to your OB before starting, especially at gut-healing doses.

Most people tolerate 5–10 g/day with no issues. Higher doses can cause mild GI upset, bloating, or constipation. People with bipolar disorder or seizure disorders should be cautious — glutamine is converted to glutamate, an excitatory neurotransmitter.