Essential Estrogens (24-hour)
See exactly how your body is producing and clearing estrogens
An at-home 24-hour urine test that measures your estrogen levels and how your body breaks them down. Useful for understandinupg irregular cycles, fertility issues, menopause symptoms, and your hormone-related cancer risk profile.
$359$766Save $407
HSA / FSA eligible
Free shippingSpecimen:Urine (24 hr)Collection:SelfCLIA-certified lab:GenovaResults:3-4 weeks
Simple Process
How it works
From order to insights in three easy steps — no doctor’s visit required.
1
Order your kit
Genova Diagnostics ships you a 24-hour urine collection kit with everything you need. It usually arrives within 1 week of purchase.
2
Collect over 24 hours at home
Collect every urine specimen over a full 24-hour period into the provided jug, then transfer a small sample into the shipping tube and mail it back in the prepaid package.
3
Get your results
Genova analyzes parent estrogens, metabolites, and ratios and delivers a detailed report covering your estrogen production and detoxification pathways.
Is This Right for You?
This test is designed for people who
If any of these apply, this test can give you clarity and peace of mind.
Have a personal or family history of breast, ovarian, uterine, or prostate cancer and want to assess your estrogen metabolism profile
Experience cyclical breast tenderness, heavy or painful periods, fibroids, or endometriosis and suspect estrogen dominance
Are in perimenopause or menopause and want a clearer picture of your hormone production and detoxification
Are on hormone therapy (HRT, birth control, bioidenticals) and want to monitor metabolism pathways
Want to track methylation and 2/16 ratios before and after lifestyle, supplement, or treatment changes
Prefer a 24-hour at-home urine collection over multiple lab draws — captures your full daily hormone output
10 markers · 4 categories
Markers evaluated
Measures every parent estrogen and every Phase 1 and Phase 2 metabolite individually, plus the key ratios that summarize how well your body is methylating and clearing estrogens.
Parent Estrogens
3 markersEstrone (E1)
Estradiol (E2)
Estriol (E3)
Phase 1 Hydroxylated Metabolites
3 markers2-Hydroxyestrone + 2-Hydroxyestradiol [2-OH(E1+E2)]
16α-Hydroxyestrone (16α-OH E1)
4-Hydroxyestrone + 4-Hydroxyestradiol [4-OH(E1+E2)]
Phase 2 Methylated Metabolites
2 markers2-Methoxyestrone + 2-Methoxyestradiol [2-MeO(E1+E2)]
4-Methoxyestrone + 4-Methoxyestradiol [4-MeO(E1+E2)]
Ratios
2 markers2-OH(E1+E2) / 16α-OHE1 Ratio
2-OH(E1+E2) / 2-MeO(E1+E2) Ratio
Common Questions