2-minute questionnaire
Answer questions about your history, prior treatments, and cardiovascular goals. No appointment needed.
InstalabRepatha · 140mg · evolocumab auto-injector
Ten seconds. Every two weeks. LDL cut by 60%.
Repatha (evolocumab) is a PCSK9 inhibitor for serious LDL reduction. Instalab handles physician review and insurance, and keeps your labs on schedule so you actually get it and stay on it.
140mgEvery 2 weeks
15%Fewer major cardiovascular events
60%Median LDL reduction
Repatha 140mg · auto-injector pen · every 2 weeks
Licensed US physician review
12,000+ patients treated
Available in all 50 states
Ongoing physician follow-up
How it works
From questionnaire to first injection.
No appointments. No clinic visits. A licensed physician reviews your case, checks what you'll pay, and, if appropriate, sends the prescription to your pharmacy.
Physician review
A licensed physician evaluates your eligibility, usually within 1 business day, and reaches out if they need anything else.
Cost check
We check your options, enroll you in Amgen's patient assistance program, and, if your plan covers Repatha, file the paperwork. You see your exact monthly cost before you commit.
Prescription sent, first injection
Your Repatha pen is sent to your preferred pharmacy. We'll walk you through self-injection and check in after your first dose.
Pricing
What you'll actually pay.
Two line items: Instalab Membership and the Repatha medication itself. No hidden fees.
Instalab Membership
Physician oversight and ongoing follow-up
$—/mo
Repatha 140mg
Evolocumab auto-injector, billed by pharmacy
Cash price$239/moWith Amgen assistance
With insurance$25–75/moTypical copay, if covered
Why pay a membership fee? Repatha needs a physician who actually knows the drug. Membership covers the visits, prescription renewals, and cost paperwork, whether you end up on insurance or the Amgen assistance program. We also recommend a lab recheck around 6 to 8 weeks and follow up on your results, though lab costs are billed separately.
Will my insurance cover Repatha?
Most commercial plans will, if you have one of: familial hypercholesterolemia, established cardiovascular disease (prior heart attack, stroke, or stented artery), or documented statin intolerance. Medicare Part D typically covers it under the same criteria. We check your plan and file the prior authorization either way. If approval is denied, Amgen's patient assistance program can bring cash cost down to ~$239/mo.
Why membership
Repatha works. Staying on it takes ongoing care.
It needs a physician who knows the drug and regular labs to confirm it's doing its job. Here's how our team handles that for you.
- Week 1Day 1–5
Physician evaluation and prescription
A licensed physician reviews your history and labs, confirms Repatha is right for you, and writes the prescription. In parallel, we enroll you in Amgen's patient assistance program and verify your insurance coverage. If you'd rather skip insurance, this takes as little as one day.
- Week 2Day 6–14
First injection at home
Your pen can be picked up at or delivered by your preferred pharmacy. We can walk you through the first injection, and check in the next day.
- Week 6–8
Confirm it's working
We recommend rechecking LDL and ApoB at a lab near you, and your physician reviews the results with you. Labs are billed separately. Rechecking is optional, but most patients want to see their numbers move.
- OngoingMonth 3+
Ongoing care and renewals
Your physician tracks your labs over time and adjusts the plan as your numbers evolve. We keep your prescription and patient assistance enrollment active, so you don't lose a year of progress to paperwork.
Without membership
Schedule a PCP visit. Wait months. Hope they know the drug. Track down patient assistance yourself. Book and chase your own labs.
With Instalab
2-minute questionnaire. Physician review within 1 business day. Insurance and patient assistance handled. Lab reminders built in.
About the medication
Ten seconds, every two weeks.
Repatha comes in a pre-filled auto-injector pen. Press it to your thigh, stomach, or upper arm, hold for about ten seconds, done. Most patients say they barely feel it.
- Takes about 10 secondsThe auto-injector pen does the work. Press, hold, done. No measuring, no syringes.
- Once every 2 weeksPick a day that works for you. Most patients do it at home on a weekend morning.
- Lab recheck recommendedWe recommend rechecking LDL and ApoB around 6 to 8 weeks so you can see your progress. Labs are optional and billed separately.
- Ongoing physician supportYour care team is a message away between doses, and your membership physician follows your labs over time.
Why Repatha
A different mechanism for serious LDL reduction.
Statins slow cholesterol production in the liver. Repatha takes a different path: it blocks PCSK9, so your liver keeps more LDL receptors active and clears more LDL from your blood. It works on its own or alongside a statin.
- Clinically proven ~60% LDL reductionAcross FOURIER and other large trials with more than 35,000 patients, Repatha consistently cut LDL by around 60% on top of or instead of a statin.
- A different mechanism than statinsRepatha blocks PCSK9, so your liver keeps more LDL receptors active and clears more LDL from your blood. It works whether or not you're on a statin.
- Simple self-injection every 2 weeksOne pre-filled auto-injector pen, about 10 seconds at home, every other week. No clinic visits, no infusions.
The FOURIER trial
Published in NEJM in 2017, FOURIER randomized 27,564 patients with established cardiovascular disease to Repatha or placebo on top of a statin. Over a median 2.2 years, Repatha reduced LDL by a median 59% and cut the composite of cardiovascular death, heart attack, stroke, hospitalization for unstable angina, or coronary revascularization by 15%.
27,564
Patients randomized
59%
Median LDL reduction
15%
Reduction in major cardiovascular events
Real results
What 60% reduction looks like in practice.
Three patients, 8 to 14 weeks in.
13548LDL mg/dL8 weeks on Repatha
“I was on rosuvastatin for years and still stuck. Repatha finally moved my numbers fast.”
11851LDL mg/dL14 weeks on Repatha
“I kept hearing to wait and recheck. This was the first time treatment actually changed my trajectory.”
15851LDL mg/dL12 weeks on Repatha
“My PCP told me I'd probably be denied and didn't want to fight it. Instalab got my prior authorization approved in nine days. I'd been putting this off for a year.”
Repatha is a prescription medicine. Important safety information applies. Side effects include injection-site reactions, cold-like symptoms, and mild muscle aches. Serious side effects are uncommon.
Common Questions
Everything people ask before starting.
Ready when you are
See your exact Repatha cost in two minutes.
Answer a few questions about your history and goals. A physician reviews your case and, if appropriate, prescribes Repatha. You'll see your exact monthly cost before you start.
No commitment to treatment.