Instalab
Zepbound · tirzepatide · once-weekly injection

Two receptors. One injection a week. 20% lighter.

Zepbound (tirzepatide) hits both GIP and GLP-1 receptors, the dual mechanism behind the largest weight loss of any FDA-approved medication. Pick the vial, KwikPen, or single-dose pen. Prescription, titration, and physician follow-up included.

20.9%Mean weight loss at 72 weeks (15mg)
2.5–15mgSix dose strengths
3 formsVial, KwikPen, single-dose pen
Zepbound Prescription Review
Zepbound · vial, KwikPen, or single-dose pen · once weekly
Licensed US physician review
12,000+ patients treated
Available in all 50 states
Ongoing follow-up
How it works

From questionnaire to first injection.

No clinic visits. A licensed physician picks the right form and starting dose, manages every titration step, and routes you to the most affordable supply.

Step 1

2-minute questionnaire

Tell us about your weight history, prior GLP-1 use, BMI, and related conditions like type 2 diabetes or obstructive sleep apnea.

Step 2

Physician review

A licensed physician confirms eligibility, picks vial, KwikPen, or single-dose pen, and writes your starting prescription, usually within 1 business day.

Step 3

Cost check and dispensing

We verify insurance and file prior authorization. If self-pay makes more sense, we shop your dose across manufacturer-direct and pharmacy options for whichever form you prefer (vial, KwikPen, or single-dose pen) and show you the lowest monthly cost before you commit.

Step 4

Titration and follow-up

Start at 2.5mg weekly and step up every 4 weeks toward your maintenance dose. We monitor side effects, manage refills, and time each dose increase with you.

Pricing

What you'll actually pay.

Two line items: Instalab Membership and the Zepbound medication itself, billed by the pharmacy or by Lilly directly. No hidden fees.

Instalab Membership

Physician oversight, titration management, and ongoing follow-up

$/mo

Zepbound

Tirzepatide injection, billed by pharmacy

Cash price$299–499/monthDepends on dosage, 2.5–15mg
With insurance$25–100/monthTypical copay for pens, if covered

Why pay a membership fee? Zepbound needs a physician who actively manages titration, side effects, and form selection across six dose strengths. Membership covers the visits, renewals, prior authorization, and shopping your dose across manufacturer-direct and pharmacy options so you land on the cheapest source for the form you want. Labs to track metabolic health are billed separately.

Will my insurance cover Zepbound?

Some commercial plans cover Zepbound for chronic weight management or moderate-to-severe obstructive sleep apnea with obesity. Coverage depends on your plan's obesity and OSA benefits, BMI, and documented weight-related conditions. We check your plan and file the prior authorization either way. If insurance won't cover it, we shop self-pay options across manufacturer-direct and pharmacy channels for whichever form you prefer.

Why membership

Zepbound works. Titration and follow-up take ongoing care.

It needs a physician who manages dose increases, side effects, and metabolic monitoring across six dose steps. Here's how our team handles that for you.

  1. Week 1Day 1–5

    Physician evaluation and prescription

    A licensed physician reviews your weight history, BMI, related conditions, and goals, then writes your starting prescription at 2.5mg. In parallel, we verify your insurance and, if you prefer to skip it, shop self-pay options across manufacturer-direct and pharmacy channels to find the cheapest source for your preferred form.

  2. Week 2Day 6–14

    First injection at home

    Your Zepbound vial, KwikPen, or single-dose pen ships from the pharmacy. We walk you through self-injection and check in after your first dose.

  3. Week 4+

    Titration every 4 weeks

    Step up by 2.5mg every 4 weeks if tolerated, toward a maintenance dose of 5, 10, or 15mg. We coordinate each refill with the new dose so you never run short.

  4. OngoingMonth 3+

    Ongoing care and renewals

    Your physician tracks weight, side effects, and metabolic labs over time, and adjusts the plan as you progress. We keep your prescription, prior authorization, and pharmacy on the same page so you don't lose months to paperwork.

Without membership

Schedule a PCP visit. Wait months. Hope they know how to titrate. Chase prior auth and manufacturer paperwork yourself. Manage side effects between appointments.

With Instalab

2-minute questionnaire. Physician review within 1 business day. Insurance and manufacturer-direct supply handled. Titration and side-effect check-ins built in.

About the medication

One injection a week. Three ways to take it.

Zepbound comes as a vial, a KwikPen, or a single-dose pen. Same medicine, three formats — pick the one that fits your routine and budget. All three are subcutaneous injections once a week, into the thigh, stomach, or upper arm.

  • Three forms, same medicineVials are drawn with a syringe and usually carry the lowest cash price. KwikPens are a multi-dose pen. Single-dose pens are one click-and-hold injection. We shop manufacturer-direct and pharmacy options for whichever form you choose.
  • Once weekly, any dayPick a weekday and stick with it. Inject any time of day, with or without food. Most patients do it the same morning each week.
  • Slow, steady titrationStart at 2.5mg for the first 4 weeks (this dose is for titration, not maintenance). Step up by 2.5mg every 4 weeks as tolerated, toward a maintenance dose of 5, 10, or 15mg.
  • Ongoing physician supportYour care team is a message away between doses, and your physician handles nausea, dose timing, and metabolic monitoring across the full plan.
Why Zepbound

Two receptors. One injection. The largest weight loss in the class.

Older weight-loss medications activate a single receptor. Tirzepatide activates both GIP and GLP-1, the two main incretin pathways that regulate appetite, insulin response, and gastric emptying. In its pivotal trial, that dual mechanism produced the largest sustained weight loss of any FDA-approved medication.

  • 20.9% mean weight loss at the top doseIn SURMOUNT-1, adults without diabetes on 15mg lost a mean 20.9% of body weight at 72 weeks versus 3.1% on placebo. The 5mg and 10mg doses produced 15.0% and 19.5% mean reductions, respectively.
  • A dual incretin mechanismTirzepatide activates GIP and GLP-1 receptors together. The combination slows gastric emptying, reduces appetite signaling, and improves insulin sensitivity more than activating either receptor alone.
  • Three formats. One medicine.Vials for the lowest cash price. KwikPens as a multi-dose option. Single-dose pens for one-click simplicity. Same tirzepatide in all three. Your physician helps pick the right form, and we shop manufacturer-direct and pharmacy options to find the cheapest source.

The SURMOUNT-1 trial

Published in NEJM in 2022, SURMOUNT-1 randomized 2,539 adults with obesity (BMI ≥ 30) or overweight (BMI ≥ 27) with weight-related conditions, without diabetes, to tirzepatide 5mg, 10mg, 15mg, or placebo, alongside diet and exercise. At 72 weeks, the 15mg group lost a mean 20.9% of body weight versus 3.1% on placebo. A separate program, SURMOUNT-OSA, supported FDA approval for moderate-to-severe obstructive sleep apnea in adults with obesity.

2,539
Patients randomized (SURMOUNT-1)
20.9%
Mean weight loss on 15mg at 72 weeks
72 wks
Trial duration
Real results

What sustained weight loss looks like in practice.

Three patients, 16 to 36 weeks in.

248209Weight (lbs)24 weeks on Zepbound

I'd tried every diet for a decade. Six months in and I'm down almost 40 pounds without thinking about food constantly.

Daniel, 42
BMI 34, on 10mg KwikPen
10mg
212168Weight (lbs)36 weeks on Zepbound

My insurance dropped GLP-1 coverage. Instalab found a self-pay source for the vials in a day and the titration plan kept the nausea manageable.

Rachel, 38
BMI 32, switched to self-pay vials
12.5mg
286258Weight (lbs)16 weeks on Zepbound

My sleep study showed moderate apnea. Insurance covered the single-dose pen, and my CPAP pressure has come down with the weight loss.

Marcus, 51
Moderate OSA, BMI 36, on 5mg single-dose pen
5mg

Zepbound is a prescription medicine. Important safety information applies. The most common side effects are nausea, diarrhea, vomiting, and constipation, usually mild and most common during dose increases. Serious side effects are uncommon.

Ready when you are

See if Zepbound is right for you in two minutes.

Answer a few questions about your weight history, BMI, and goals. A physician reviews your case, picks the right form and starting dose, and, if appropriate, prescribes Zepbound. We handle titration, refills, and follow-up from there.

No commitment to treatment.