SBI Protect® Powder 2.5 g by Ortho Molecular Products

Frequent loose stools after antibiotics or travel, irritable bowel syndrome with diarrhea, and post-infectious gut upset are where bovine immunoglobulin powder earns its keep. If your stool testing shows elevated fecal calprotectin (a marker of gut inflammation) or low secretory IgA (the antibody your gut secretes into the lumen), this is a targeted option. The twice-daily 2.5 g scoop (5 g/day) is a clinically used dose; expect steadier stools within 2 to 4 weeks, with fuller symptom settling by 4 to 8 weeks.

These concentrated IgG antibodies are not systemically absorbed; they act inside the intestines. They bind bacterial fragments like LPS (endotoxin from gram‑negative bacteria), viral particles, and food antigens, which keeps them from triggering immune cells and irritating the lining. By neutralizing those triggers, stool frequency and urgency often drop, hs-CRP (a blood inflammation marker) may improve in responders, and barrier function can normalize, which you’ll feel as less bloating and more formed stools.

Mix one scoop in cool or room‑temperature liquid twice daily. Hot liquids can denature proteins, so keep it below coffee/tea temperatures. Take with or without food. Because it can bind substances in the gut, separate from medications and iron by 2 hours. If you’re sensitive, start with one scoop daily for a week, then increase. Maintain 5 g/day during active symptoms; some step down to 2.5 g/day once stable.

Avoid if you have a confirmed allergy to beef products or alpha‑gal syndrome (red‑meat allergy). It is dairy‑free, but anyone with severe milk or serum protein reactions should discuss with a clinician first. Not enough data for pregnancy or breastfeeding; get medical guidance. If you’re on complex biologic or immunosuppressive therapy, coordinate timing with your prescriber to avoid unintended binding in the gut.