Magnesium Glycinate 120 mg by Pure Encapsulations

If you’re looking for a gentle, well-absorbed magnesium glycinate for sleep, muscle tension, or steady mood, this fits. It’s a practical pick if your diet is light on greens, nuts, and legumes, or if your Magnesium, RBC (a better gauge of tissue magnesium than serum) trends low. Athletes with frequent cramps, high-stress professionals with tight shoulders, and people who sleep lightly often feel the difference. The 120 mg per capsule is a maintenance-level dose; for clear deficiency, clinicians often start higher and step down once symptoms and labs stabilize.

Magnesium drives ATP production (your cells’ energy currency) and steadies nerve firing by calming NMDA receptors (the brain’s main excitatory switch). Glycinate is magnesium bound to glycine, an amino acid with a mild calming effect, which helps tolerance and nighttime use. Compared with oxide or citrate, this form is better absorbed and less laxative, so more of the 120 mg ends up in tissues. In practice, people notice looser muscles and smoother sleep onset within 1 to 2 weeks once daily intake is consistent.

Take 1 to 4 capsules daily with food, splitting doses if you use more than one capsule. Evening dosing is sensible if sleep is your target; spread morning and evening if daytime tension or headaches are the issue. If you’re repleting after a low Magnesium, RBC result, start at the higher end for 2 to 4 weeks, then taper to the lowest number that maintains benefits. Recheck Magnesium, RBC in 4 to 8 weeks to confirm you’ve landed in a good place.

Separate magnesium by at least 4 hours from levothyroxine, quinolone or tetracycline antibiotics, and bisphosphonates (it binds these drugs and blocks absorption). Loop and thiazide diuretics (water pills) can lower magnesium; proton pump inhibitors used long term often do too. It can modestly lower blood pressure, so monitor if you’re on antihypertensives. If you have significant kidney disease, or a history of high magnesium, use only with clinician guidance. Pregnancy and breastfeeding: generally considered appropriate at dietary doses, but confirm your total daily magnesium with your obstetric clinician.