NAC 600mg by Pure Encapsulations

If your Glutathione or GGT (gamma‑glutamyl transferase, a marker of oxidative stress and liver load) suggests your antioxidant defenses are strained, NAC 600 mg is a practical first step. It fits athletes in heavy training, adults with high pollution exposure, frequent acetaminophen use, or low protein intake, where cysteine can be limiting. If your liver enzymes (ALT, AST) run high, clinicians often try NAC while they address root causes. For established deficiency, higher short‑term dosing under guidance is common, then step down.

N‑acetyl cysteine is a stable, well‑absorbed form of cysteine, the rate‑limiting building block for glutathione (the cell’s main antioxidant). By raising intracellular glutathione, NAC helps neutralize reactive oxygen species and supports phase II detoxification (the liver’s process of attaching glutathione to toxins so they can be excreted). It also breaks disulfide bonds in mucus, which explains its use as a mucolytic in respiratory care. In responders, oxidative stress markers and hs‑CRP (a general inflammation marker) often improve within 2 to 6 weeks.

Take 1 capsule between meals, 1 to 3 times daily. Between meals improves uptake because cysteine competes with other amino acids from protein. For steady glutathione repletion, many adults use 600–1,200 mg per day for 4 to 12 weeks, then reassess labs. If you’re targeting thick mucus, split dosing (morning and mid‑afternoon) is practical. Pairing with glycine and selenium can further support glutathione recycling, but check your Selenium and RBC Magnesium first to avoid overshooting.

Skip NAC with nitroglycerin or isosorbide, since it amplifies vasodilation and can cause severe headaches and low blood pressure. Use caution with blood thinners or high‑dose fish oil because NAC has mild antiplatelet effects; monitor if you bruise easily. Oncology patients should not self‑supplement antioxidants around chemo or radiation without oncologist approval. Asthma is fine with oral NAC in most people, but stop if you notice wheeze. Pregnancy and nursing: use only with clinician guidance.