Magnesium Bisglycinate 200 mg by Thorne

Magnesium glycinate is a fit if your Magnesium, RBC or Serum Magnesium is low or low‑normal and you have sleep trouble, muscle tightness, migraines, or high training loads. It also helps if you take a proton‑pump inhibitor for reflux, a diuretic for blood pressure, or drink alcohol regularly, all of which deplete magnesium. Vegans with low nut/seed intake and people under chronic stress often land here too. If constipation is your main issue, citrate is better; glycinate is for absorption and calm, not laxation.

This form binds magnesium to glycine, an amino acid that is calming at GABA receptors (the brain’s main braking system). The chelate shields magnesium from gut acids, improving uptake versus oxide and reducing loose stools. Once absorbed, magnesium stabilizes ATP (the body’s energy currency), relaxes muscle by balancing calcium entry into cells, and tempers the stress response. Better levels often show up as steadier sleep and fewer tension cramps.

Each scoop provides 200 mg elemental magnesium. Mix with water once daily for maintenance, or twice daily if your level is low and your clinician agrees. Evening is popular for sleep; split morning and night for muscle symptoms. Take with a small snack if you have a sensitive stomach. Repletion usually takes 2 to 4 weeks; sleep and cramp benefits often appear within 3 to 14 days. Recheck Magnesium, RBC after 4 to 8 weeks.

Separate magnesium glycinate by 4 hours from levothyroxine, tetracycline or fluoroquinolone antibiotics, and bisphosphonates, since minerals bind these drugs and block absorption. Use extra caution with significant kidney disease, where magnesium can accumulate. If you’re on high‑dose calcium or iron, take them at a different time of day. For ongoing reflux on proton‑pump inhibitors, this is a smart add, but still confirm low levels with Magnesium, RBC.