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DHEA-S

Dried Urine Test
An adrenal derived hormone that reflects reserve, resilience, and healthy aging.
4.8 (4,943 reviews)
Tested by Precision Analytical
Physician-reviewed results
Results in 7–10 business days
How it works
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No prescription or your own doctor's order needed
Self-collect at home
Kit shipped directly to you
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Explained with clear next steps, no medical jargon

About DHEA-S

DHEA sulfate is a stable storage form of DHEA produced primarily by the adrenal glands. It serves as a precursor for both estrogen and testosterone and plays a role in immune regulation, mitochondrial function, and stress adaptation. Levels peak in early adulthood and decline progressively with age, making it a marker of biological aging rather than acute stress. Chronically low levels are associated with frailty, reduced stress tolerance, and poor recovery, while elevated levels may reflect supplementation or adrenal hyperactivity. Interpretation requires age and sex context.

Frequently Asked Questions

DHEA-S Testing Options

$465

An at-home dried-urine panel that maps sex and adrenal hormones plus metabolites, cortisol rhythms, melatonin, and markers of nutrient/oxidative-stress status.

Includes 56 biomarkers:
DHEA-Sb-Pregnanediola-PregnanediolE1E2
$615

An at-home hormone and stress test that maps your sex hormones and daily cortisol pattern so you can understand what’s driving your energy, mood, sleep, and weight.

58 biomarkers
FSA/HSA eligible
No Rx needed
HIPAA compliant