DHEA sulfate is a stable storage form of DHEA produced primarily by the adrenal glands. It serves as a precursor for both estrogen and testosterone and plays a role in immune regulation, mitochondrial function, and stress adaptation. Levels peak in early adulthood and decline progressively with age, making it a marker of biological aging rather than acute stress. Chronically low levels are associated with frailty, reduced stress tolerance, and poor recovery, while elevated levels may reflect supplementation or adrenal hyperactivity. Interpretation requires age and sex context.
DHEA-S is included in these pre-built panels.
An at-home dried-urine panel that maps sex and adrenal hormones plus metabolites, cortisol rhythms, melatonin, and markers of nutrient/oxidative-stress status.
An at-home hormone and stress test that maps your sex hormones and daily cortisol pattern so you can understand what’s driving your energy, mood, sleep, and weight.
58 biomarkers