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The big picture: Cystatin C is a protein naturally produced by the body, playing a key role in inhibiting the breakdown of other proteins. It is typically filtered from the blood by the kidneys and excreted in the urine. Elevated blood levels of cystatin C can be indicative of reduced kidney function, as the kidneys are responsible for its regulation.

Filtration process and kidney health indicator: This protein undergoes filtration through the glomerulus - a tiny network of blood vessels at the start of each nephron in the kidney. It is then reabsorbed and broken down by renal cells, resulting in minimal urinary excretion.

Cystatin C vs creatinine: Creatinine, a breakdown product of creatine phosphate in muscle, is widely used in kidney function t