Histamine Test Blood

A signaling molecule that regulates allergy, stomach acid, and brain function, with effects ranging from itching to inflammation.

H1 receptors control allergic responses, including skin itching (pruritus), nasal congestion, swelling, and bronchoconstriction (airway narrowing). They also influence wakefulness and alertness.
H2 receptors primarily regulate stomach acid production and influence heart function. H2 blockers like famotidine reduce acid reflux by targeting this receptor.
H3 receptors are located mostly in the brain and help regulate the release of other neurotransmitters like dopamine and serotonin, affecting wakefulness, appetite, and cognition.
H4 receptors are primarily involved in immune cell function, influencing allergic inflammation and autoimmune responses.

References

13 studies