Liver Function Panel

Measures liver enzymes, proteins, and bilirubin to assess liver health and detect damage.

Performing LabsQuest Diagnostics, Labcorp

Specimen TypeBlood

Collection LocationAt Home or Lab Visit

Fasting RequiredNo

About Liver Function Panel

The Liver Function Panel evaluates how well your liver is working by measuring enzymes, proteins, and bilirubin levels that reflect liver cell health, bile flow, and your body’s ability to process and clear waste. It includes key markers like ALT, AST, ALP, and GGT, which can signal inflammation, damage from toxins or infections, or early signs of liver disease. The panel also measures bilirubin (both total and direct) to assess how effectively your liver is clearing waste, and albumin and total protein to evaluate your liver’s role in nutrient transport and overall protein balance.

This test is often ordered when you have symptoms like fatigue, abdominal pain, jaundice (yellowing of the skin or eyes), or unexplained weight loss. It’s also useful for monitoring liver health if you take medications that can affect the liver, consume alcohol regularly, or have conditions like hepatitis or fatty liver disease. By combining multiple markers, the panel offers a comprehensive snapshot that can help catch problems early—before symptoms become severe or irreversible damage occurs.

9 Biomarkers Included

Alanine Aminotransferase

An enzyme released from liver cells that reveals early signs of liver stress, inflammation, or damage.

Aspartate Aminotransferase

An enzyme involved in amino acid metabolism that signals liver or heart damage when released into the bloodstream.

Alkaline Phosphatase

An enzyme important for many processes in your liver and bones; high levels can indicate disease in these areas.

Gamma Glutamyl Transferase

An enzyme that breaks down toxins and signals liver stress or bile duct issues.

Total Bilirubin

A byproduct of the breakdown of blood cells that reflects liver processing and signals risks for liver disease, bile duct problems, and red blood cell breakdown.

Direct Bilirubin

A water-soluble substance that reflects how well the liver processes waste and signals liver or bile duct problems.

Indirect Bilirubin

A blood pigment that reflects red blood cell breakdown and liver processing, linked to both protective antioxidant effects and risks when elevated.

Albumin

A protein that maintains fluid balance and carries hormones, vitamins, and drugs through your bloodstream.

Total Protein

A combined level of all proteins in the blood, used to assess nutritional status, liver function, and chronic inflammation.