Rosuvastatin is one of the most effective interventions for lowering ApoB & LDL cholesterol, stabilizing plaque, and reducing long-term cardiovascular risk.
Rosuvastatin delivers powerful ApoB & LDL reduction at a low dose, while also improving endothelial health and reducing inflammation - key drivers of heart and brain aging.
Your prescription is evaluated and approved by a board-certified lipidologist same day. This ensures this medication is safe for you.
Your medication is filled through licensed U.S. pharmacies that follow strict protocols for quality, consistency, and safety, so every tablet meets the highest standard.
A daily 5 mg dose of rosuvastatin significantly reduces ApoB and LDL, two of the most predictive markers of heart disease risk. Studies show average reductions of 35-42%, even in people with type 2 diabetes or prior statin intolerance12345.
Large clinical trials show rosuvastatin at low doses meaningfully lowers the risk of heart attacks, strokes, and cardiovascular death, even in people with no history of cardiovascular disease. Risk reduction ranges from 21-24% over 5-9 years, compared to placebo78.
In addition to targeting ApoB and LDL cholesterol, rosuvastatin 5 mg also lowers triglycerides by 24-30%, reduces total cholesterol by 27–33%, and modestly raises HDL cholesterol, supporting a healthier long-term lipid balance34.
Rosuvastatin 5 mg is generally well tolerated, with a low risk of muscle or liver-related side effects. It's often used successfully in people who couldn't tolerate other statins. Discontinuation due to side effects is rare1234.
Not seeing expected results? You can adjust your medication or consult a physician through our Heart Health Program.
Rosuvastatin blocks cholesterol at the source: your liver.
Your liver is the main factory for cholesterol in your body. Rosuvastatin works by blocking a key enzyme in that factory called HMG-CoA reductase, which slows down how much cholesterol your liver can make. When cholesterol production goes down, your body builds fewer cholesterol-carrying particles that contribute to artery damage over time.
These particles include LDL (low-density lipoprotein), as well as others like VLDL (very low-density lipoprotein) and Lp(a). What they all have in common is a structural protein called Apolipoprotein B (ApoB). You can think of ApoB as a tag that marks every particle capable of depositing cholesterol into artery walls. So when rosuvastatin reduces cholesterol production, it ultimately helps lower the number of ApoB-containing particles in your bloodstream.
Unlike many statins, rosuvastatin is hydrophilic (water-soluble), which means it doesn't diffuse into other tissues like muscle or brain. Instead, it stays focused in the liver where it's needed most and is efficiently absorbed with the help of a specialized transporter called SLCO2B1. This ensures powerful cholesterol-lowering effects with fewer off-target side effects.
Rosuvastatin 5 mg is a low-dose prescription statin designed to lower LDL cholesterol and ApoB, a key driver of cardiovascular risk. Although this dose is considered gentle, rosuvastatin still affects cholesterol production, liver metabolism, and on rare occasions blood sugar regulation.
To ensure safe and responsible prescribing, we require recent lab results showing your LDL Cholesterol or ApoB levels before initiating treatment. If you haven't had this testing done, we'll guide you through how to get it.
If you want more hands-on care, we offer the Heart Health Program, which is a physician-led option that includes comprehensive lab testing, 1-on-1 medical support, and a personalized approach to managing both heart and metabolic health.
