Serrapeptase by NutraMedix, LLC

After dental work or during a sinus flare, many people search serrapeptase dosage for swelling and pressure. This proteolytic enzyme is most relevant for short-term use in post‑procedure swelling, clogged sinuses with thick mucus, and tendon or overuse aches where rest and rehab are already in place. If you track inflammation with hs-CRP (a blood marker of systemic inflammation), you can use it as a rough read on response, though pain and function matter more day to day.

Serrapeptase breaks down proteins that make up thick mucus and some of the debris around inflamed tissues. In small trials it reduced nasal mucus thickness and post‑procedure swelling, which is why people reach for it in sinusitis and after dental surgery. It also has mild fibrinolytic activity, meaning it can help break down fibrin (a clotting protein). That is the theoretical reason for both the de‑puffing effects and the bleeding‑risk cautions.

Take it on an empty stomach, at least 30 minutes before meals, with a full glass of water; food proteins can inactivate the enzyme. The label suggests one to two capsules, one to three times daily. Clinically, enteric‑coated units (often listed as SPU or SU) guide dosing, but this blend doesn’t disclose units, so start low, assess for 7 to 14 days, and stop if you see no clear benefit.

Avoid if you use blood thinners like warfarin, apixaban, rivaroxaban, or antiplatelets such as aspirin or clopidogrel, or if you have a bleeding disorder or active ulcer, due to added bleeding risk. Stop at least 7 days before surgery. Pregnancy and breastfeeding: avoid for lack of safety data. Separate from antibiotics by a few hours to minimize stomach upset and theoretical interactions.