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Thorne

L-Glutamine Powder 5 g by Thorne

513 grams · 90-day supply
An amino acid for gastrointestinal and immune support and post-exercise recovery.
$XX.XX$67.00retail
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Gluten FreeSoy FreeDairy FreeMilk Free

Thorne L-Glutamine Powder overview

L-Glutamine Powder is built for adults who put their bodies through a lot. Athletes deep in heavy training blocks, people seeking everyday support for digestive comfort and gut-barrier integrity, and adults navigating prolonged periods of physical stress or stretches of inadequate nutrition. It is also a sensible option for anyone who wants a clean, single-ingredient amino acid powder that mixes into water or juice without flavoring, sweeteners, or fillers.

L-glutamine is the most abundant amino acid in the bloodstream and is concentrated in the gastrointestinal tract, where the cells lining the gut (enterocytes) use it as a primary fuel. Adequate glutamine supports the integrity of the intestinal lining and the tight junctions between cells, which underpins healthy gut-barrier function. Glutamine also fuels rapidly dividing immune cells and serves as a precursor to glutathione, an endogenous antioxidant. Plasma glutamine can fall during prolonged exhaustive exercise and extended physical stress, and supplementation helps restore those levels.

Mix one scoop (5 g) into at least 8 ounces of cool water, juice, or a beverage of your choice once daily, with or without food. If you train hard, taking it within an hour after a session is a reasonable habit; otherwise any consistent time of day works. The powder is unflavored and dissolves cleanly. Most people notice changes in digestive comfort and recovery over two to four weeks of daily use; if you have not noticed a shift by eight weeks, reassess with your clinician.

Review the warnings below before starting, especially if you are pregnant, breastfeeding, taking prescription medications, or under the care of a clinician for any condition.

Frequently asked questions

What does L-glutamine actually do?

L-glutamine is the most abundant amino acid in the bloodstream and the preferred fuel for the cells that line the gastrointestinal tract. It supports a healthy intestinal lining, contributes to gut-barrier function via tight junctions, fuels immune cells, and serves as a precursor to glutathione.

How long does L-glutamine take to work?

Most people notice changes in digestive comfort and post-exercise recovery within two to four weeks of daily use. Give it a fair eight-week trial before deciding whether it is doing anything for you, and reassess with your clinician if nothing has shifted.

When should I take L-glutamine, before or after workouts?

Either works. Many people take it within an hour after training to support recovery, but the more important variable is consistency. Pick a time of day you will actually remember and stick with it.

Does L-glutamine help with muscle recovery or performance?

Glutamine supports post-exercise muscle cell repair and helps restore plasma glutamine levels that are depleted after prolonged exhaustive exercise. It is not a stimulant and is not marketed as a performance enhancer; think of it as a recovery-support amino acid.

Is L-glutamine the same as MSG, and will it raise glutamate?

No. L-glutamine and monosodium glutamate (MSG) are different molecules. Glutamine can be converted to glutamate in the body as part of normal amino acid metabolism, but supplementing within the typical 5 g daily dose does not produce MSG-like effects in healthy adults.

Can I take L-glutamine with other supplements?

L-glutamine is generally compatible with common supplements like protein powders, creatine, and multivitamins. If you take prescription medications or follow a clinician-directed diet, review the warnings section and talk with your prescriber before adding it.

Are there side effects?

Most adults tolerate 5 g daily without issue. Some people experience mild gas or bloating when starting; this usually settles within a few days. Review the warnings section before starting, particularly if you have liver or kidney concerns, are pregnant or breastfeeding, or are in active cancer treatment.

How to take it & ingredients

Suggested use: Mix 1 scoop with at least 8 ounces of water, juice, or preferred beverage daily or as recommended by your health professional.
Active ingredients
1 scoop = 5.7 grams per serving · 90 servings
L-Glutamine
5 g