This test is most useful if any of these apply to you.
Every day your body takes in traces of the chemicals around you: weed killers on produce, softeners in plastic, preservatives in lotion, and fumes from traffic and cleaning products. Most of these leave your body within hours to a couple of days, passing out through your urine. This panel captures a snapshot of that recent traffic.
It measures the breakdown products of dozens of pesticides, plastics, and consumer chemicals from a single urine sample. It cannot diagnose a disease or prove that any chemical is harming you. What it can do is show which exposures are actually reaching your body, so you can find and reduce the sources that matter most to you.
The pesticide and herbicide markers make up the largest part of the panel. A cluster of organophosphate insecticide breakdown products (the dialkyl phosphates) reflects your recent contact with a whole class of bug sprays used on crops and in homes. Separate markers track the weed killers glyphosate and 2,4-D, the corn herbicide atrazine, a shared breakdown product of pyrethroid insecticides, and a leftover from the long-banned pesticide DDT.
Another group covers the chemicals in plastics and personal care products. Phthalate markers reflect the softeners that make plastic flexible and that carry fragrance in lotions and shampoos. Bisphenol A comes from hard plastics and receipt paper, parabens from cosmetic preservatives, and triclosan from antibacterial soaps and toothpaste.
A further set of markers reveals exposure to volatile organic compounds (chemicals that evaporate easily into the air), including benzene, toluene, xylene, and acrylonitrile. Your body attaches these to small molecules and excretes them, and those excreted forms show up here as mercapturic acids and hippuric acids. The panel also tracks perchlorate, which can interfere with how your thyroid takes up iodine, plus a breakdown product of flame retardants.
A final pair of markers, tiglylglycine and 2-hydroxyisobutyric acid, are not exposure markers at all. They are byproducts of your body's energy and protein metabolism that some frameworks read as early signs of metabolic strain, though this use is exploratory. Creatinine is measured alongside everything to correct for how dilute or concentrated your urine was.
The point of testing so many chemicals at once is to see your exposure as a pattern. Nearly everyone tested shows several chemicals at once, so a single detected chemical rarely means much on its own. What matters is which groups stand out together and how your levels compare with the general population.
| Pattern | What It May Suggest |
|---|---|
| Many classes detected at low levels | The expected background pattern of modern life, useful as a baseline to track over time. |
| Pesticide markers stand out | Points toward diet or your local environment, such as produce, water, or nearby agriculture. |
| Volatile-compound markers high, especially the acrylonitrile marker | Strongly suggests tobacco smoke exposure, first- or secondhand. |
| Plastic and personal-care markers high | Points toward packaged food, plastic storage, and cosmetics as the main drivers. |
Comparison with the population matters because being detectable is not the same as being high. In one large European survey, levels high enough that a health concern could not be ruled out were seen for 15 of the measured chemicals, including a pyrethroid breakdown product in 36% of children. If the metabolic byproduct markers are elevated alongside high exposure markers, some practitioners read that as possible metabolic strain, but the human evidence for that link is preliminary and it should not be treated as a diagnosis.
Because these chemicals clear quickly, your results reflect the days just before the test, which is good news: change your habits and your numbers usually follow. If a group stands out, focus your effort there. High plastic markers point to food packaging and storage, while high pesticide markers point to washing produce, choosing organic for the foods you eat most, and checking your water.
One urine sample is a snapshot, not your long-term average. To act on a result with more confidence, collect a first-morning sample and retest a second time before concluding that a level is truly high. Retest six to twelve weeks after changing a source to confirm the direction is what you wanted, and a yearly baseline makes sense if you are tracking exposure over time. If your perchlorate or occupational solvent markers are high, add a thyroid check or involve an occupational health or toxicology clinician.
The whole panel shares a few blind spots. Every marker here is short-lived, so a single sample can miss a large exposure from last week and catch a small one from this morning. Hydration shifts every number at once, which is why creatinine is measured to adjust for it. And a detected chemical only proves contact, not harm, since these chemicals are so widespread that nearly everyone tests positive for many of them.
Repeat testing also shows that some markers are steadier than others. Bisphenol A in particular bounces around a lot from sample to sample, so one reading is a weak guide to your usual level, while several phthalate markers hold moderately steady over time.
Environmental Toxins + Consumer Chemicals is best interpreted alongside these tests.