Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that your body cannot produce on its own. It must be obtained through food, primarily fruits and vegetables such as citrus, berries, bell peppers, and leafy greens. It’s best known for preventing scurvy, a disease caused by severe deficiency that leads to fatigue, bleeding gums, poor wound healing, and joint pain due to weakened blood vessels and connective tissue.
At its core, vitamin C acts as a biological reducing agent, a compound that donates electrons to other molecules. This makes it a powerful antioxidant, helping neutralize free radicals, unstable molecules that can damage cells and DNA. Antioxidants like vitamin C are critical for preventing oxidative stress, a process linked to aging and chronic diseases.
Vitamin C also serves as a cofactor, a helper molecule, for several enzymes. These enzymes support important processes, including:
Vitamin C deficiency may occur in people with very limited diets, substance use disorders, malabsorption, or chronic illness. Early symptoms include fatigue, bruising, bleeding gums, and poor wound healing. In children, deficiency can cause joint pain or refusal to walk due to bleeding in bones or muscles.
While vitamin C is often marketed to boost immunity and prevent colds, evidence does not support widespread supplementation for this purpose. In healthy individuals, taking large doses does not reduce the frequency of colds. However, it may shorten their duration slightly in some people.
High doses of vitamin C (typically above 1000 mg per day) may cause digestive upset, including bloating or diarrhea. In people prone to oxalate kidney stones, excess vitamin C may increase risk by converting into oxalate, a compound that can crystallize in the urinary tract. People with iron overload conditions (like hemochromatosis) should also be cautious, as vitamin C enhances iron absorption and may worsen toxicity.