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Ortho Molecular Products
L-Glutathione 250 mg by Ortho Molecular Products
60 capsules · 60-day supply
Powerful Antioxidant Support for Cellular Health and Detoxification$XX.XX$64.88retail
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Vegan·Vegetarian·Gluten Free·Artificial Color Free·Artificial Flavor Free
Ortho Molecular Products L-Glutathione overview
If your lifestyle or labs suggest higher oxidative stress, a glutathione supplement can help. Think frequent alcohol use, urban pollution exposure, hard training weeks, or a diet light on sulfur-rich foods like eggs and crucifers. People with low whole-blood glutathione or a higher Gamma-Glutamyl Transferase (GGT, an enzyme that tends to run higher when glutathione turnover is stressed) are good candidates. The 250 mg here is a maintenance dose; those with established deficiency often use 500–1,000 mg short term, then step down.
Glutathione is the cell’s primary antioxidant, a tripeptide that neutralizes free radicals and keeps other antioxidants like vitamins C and E in their active form. It also powers glutathione S‑transferase (the enzyme family that tags toxins so the liver can excrete them) and helps immune cells function by maintaining redox balance, the cell’s internal electron flow. Setria L‑glutathione has human data showing rises in blood glutathione within 4 to 12 weeks, with modest drops in oxidative markers in responders. The skin‑lightening buzz is inconsistent and mostly seen with higher doses or non‑oral routes.
Take one capsule daily, ideally on an empty stomach or away from protein to minimize competition for transport. Pairing with vitamin C can help keep glutathione in its reduced, active state. If your goal is repletion, many clinicians start at 500 mg per day for 4–8 weeks, then move to 250 mg. Track changes with whole-blood glutathione if available, and follow liver enzymes like ALT and AST if you’re taking it for liver stress.
If you’re in active chemotherapy or about to begin radiation, clear antioxidants like L‑glutathione with your oncology team; timing can matter with drugs that rely on oxidative stress. Pregnancy and breastfeeding lack strong safety data, so avoid unless your clinician advises. Asthma triggered by sulfur compounds is rare with oral dosing but warrants caution. Mild nausea or loose stools can occur; reduce the dose or take with a small snack if sensitive.
Frequently asked questions
Does oral glutathione actually raise levels?
Yes. Setria L‑glutathione has human studies showing increases in blood glutathione with daily dosing, typically within 4–12 weeks. Not everyone responds equally; baseline status and diet matter.
How long does glutathione take to work?
Most people see lab changes within 4–12 weeks. Symptom changes, like less post‑workout soreness or better recovery from alcohol, can appear sooner but are subjective.
Should I take NAC or glutathione?
NAC (N‑acetylcysteine) is a precursor that helps your body make glutathione. L‑glutathione provides the finished molecule. If you tolerate sulfur poorly, starting with glutathione can be gentler; if cost is a concern, NAC is cheaper.
What time of day should I take glutathione?
Morning on an empty stomach is common, but consistency matters more than clock time. If you get nausea taking it fasted, use a small snack and take it the same way daily.
Does glutathione lighten skin?
Evidence for skin lightening with oral glutathione is mixed and usually tied to higher doses or non‑oral routes. Take it for antioxidant and detox enzyme support, not for guaranteed pigment changes.
Is glutathione safe in pregnancy?
There is not enough high‑quality safety data in pregnancy or breastfeeding. Avoid unless your clinician specifically recommends it for a clear indication.
Can I take glutathione during chemotherapy?
Do not start without your oncologist’s approval. Antioxidants can interact with treatments that use oxidative stress to kill cancer cells. Timing and specific drugs matter.
What side effects should I expect?
Glutathione is generally well tolerated. Occasional nausea, bloating, or loose stools can occur, especially at higher doses. Reducing the dose or taking with a small snack usually solves it.
How to take it & ingredients
Suggested use: 1 capsule per day or as recommended by your health care professional.
Active ingredients
1 capsule per serving · 60 servings
L-Glutathione
Reduced (Setria)
Reduced (Setria)
250 mg
Other ingredients: Hypromellose (Natural Vegetable Capsule), Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate
Certifications
Benefits
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