Pro Bono® by Ortho Molecular Products

If your DEXA scan shows low bone density and you want a non-drug option, strontium citrate for bone density paired with calcium, vitamin D3, and vitamin K2 is a practical stack. This blend fits postmenopausal women, men with age-related bone loss, adults on long-term steroids, and those with low dietary calcium. Check Vitamin D, 25-Hydroxy before starting; the built-in D3 here is a maintenance dose, so established deficiency usually needs higher D3 short term, then this for upkeep.

Strontium slows bone breakdown and nudges formation, which can raise DEXA readings within 6–12 months. The catch is that strontium sits in bone and can overestimate DEXA, so track fracture risk and bone turnover markers like CTX (bone resorption) and P1NP (bone formation), not the scan alone. Vitamin K2 MK-7 activates osteocalcin (the protein that locks calcium into bone) and Matrix Gla Protein (which helps keep calcium out of arteries). Calcium hydroxyapatite mirrors natural bone mineral, magnesium supports bone matrix, and boron helps vitamin D signaling.

Use two packets daily, morning and evening, with food. For best strontium uptake, separate it from calcium-rich meals or mineral supplements by about two hours. If you’re on levothyroxine (thyroid hormone) or quinolone/tetracycline antibiotics, separate this mineral-heavy formula by at least four hours to avoid binding. Recheck Vitamin D, 25-Hydroxy and, if available, CTX or P1NP after 3–6 months to gauge effect and adjust.

Vitamin K (K1 and K2) reduces the effect of warfarin and similar vitamin K–dependent anticoagulants, so skip this if you rely on those drugs unless your prescriber actively manages dosing and INR. Minerals in this formula can also interfere with absorption of bisphosphonates taken orally; take those medications at a different time of day per your clinician’s instructions.

Avoid in pregnancy due to added preformed vitamin A (palmitate) and uncertain strontium safety. Use caution if you form calcium kidney stones, have high blood calcium, sarcoidosis, or significant kidney disease. If your Omega-3 Index and hs-CRP (an inflammation marker) are high, address those risks separately; they matter for fracture risk but aren’t fixed by calcium alone.