Magnesium Citrate 150 mg by Pure Encapsulations

If you get calf cramps at night, have low intake of nuts/greens, or want gentler regularity, magnesium citrate is a practical pick. It’s well suited if your Serum Magnesium or RBC Magnesium is low or low-normal, you’re an endurance athlete losing minerals in sweat, or you’ve been on long-term acid-reducing meds and suspect depletion. Compared with other forms, this one often helps with constipation while you replete stores.

Magnesium is a cofactor for hundreds of enzymes that turn food into ATP (the cell’s energy currency) and regulate nerve signaling and muscle contraction. The citrate form dissolves easily in water, which improves absorption versus oxide. In the gut, unabsorbed citrate holds water, softening stools; in muscle and nerves, adequate magnesium steadies excitability, which is why cramps and twitching often ease as levels normalize.

Each capsule provides 150 mg. Most adults use 1–3 capsules daily with food, split morning and evening to improve absorption and reduce GI upset. For relaxation or nighttime cramps, take part of the dose in the evening. Bowel regularity usually shifts within 24–48 hours; tissue repletion and cramp improvement take 2–4 weeks, with lab changes in 4–8 weeks. If loose stools occur, lower the dose or switch to magnesium glycinate.

Magnesium binds certain drugs and blocks their absorption. Separate by at least 2–4 hours from levothyroxine, tetracycline or quinolone antibiotics, and oral bisphosphonates. It can also reduce absorption of some iron supplements—take them at different times. If you use other laxatives, additive effects can cause diarrhea and dehydration, so adjust thoughtfully.

Avoid magnesium citrate with significant kidney disease or if you’ve had high magnesium on labs. If you have a sensitive gut, frequent loose stools, or active diarrhea, choose magnesium glycinate, which is less laxative. For migraine prevention or sleep where GI tolerance matters, glycinate or threonate are often better fits. In pregnancy, ask your clinician before using laxative-leaning forms.