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Ortho Molecular Products
Lipoic Acid 300 mg by Ortho Molecular Products
60 capsules · 60-day supply
Versatile Antioxidant in Both Water-Soluble and Fat-Soluble Cell Environments$XX.XX$69.21retail
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10% below MSRP3rd-party tested for purity & potencyFree shipping $50+
Gluten Free·Corn Free·Yeast Free·Artificial Color Free·Artificial Flavor Free
Ortho Molecular Products Lipoic Acid 300 mg overview
Ortho Molecular Lipoic Acid 300 mg is the once-daily, standard-release entry point for people who want to add alpha-lipoic acid to their routine without committing to twice-daily dosing. It fits adults who want a single capsule, are starting from scratch with ALA, or are using it as a maintenance dose after working through a higher-dose protocol with their clinician. If you are already running a 600 mg controlled-release twice-daily routine and want to keep that pattern, the XYMOGEN ALAmax CR 60-tablet is the better match; this product is the simpler companion when one capsule a day is the goal.
Alpha-lipoic acid is one of the most versatile antioxidants because it works in both water-soluble and fat-soluble cell environments. As a short-chain fatty acid, it can be absorbed by fatty tissues and stay soluble in water, and it readily crosses the blood-brain barrier after absorption in the small intestine. It regenerates vitamins C and E, raises intracellular glutathione (the cell's master detoxifying tripeptide), and acts at AMPK, a regulator of cellular energy. Biotin is paired with ALA at 300 mcg because high-dose ALA can compete with biotin transport; topping up biotin keeps that pathway covered.
Take 1 capsule daily. Absorption is better on an empty stomach; if you find that uncomfortable, take it with a small snack instead. Separate by at least two hours from iron, magnesium, and calcium since alpha-lipoic acid can bind minerals. Plan on six to twelve weeks of consistent dosing before judging the response.
If you take prescription medications, are pregnant or breastfeeding, or are receiving cancer treatment, talk to your clinician before starting and review the warnings below.
Frequently asked questions
What does alpha-lipoic acid actually do?
It works as a dual-soluble antioxidant in both watery and lipid cell compartments, regenerates vitamins C and E, increases glutathione, and acts at AMPK as part of cellular energy regulation. Effects build with consistent dosing rather than appearing acutely.
Is 300 mg the right dose for me?
300 mg once daily is a standard maintenance or starting dose. Higher daily totals exist for specific clinician-directed protocols. If you are unsure which to use, start at 300 mg, observe how you respond, and discuss adjustments with a clinician.
How does this compare to controlled-release ALA?
This is standard-release once daily. Controlled-release products like XYMOGEN ALAmax CR are typically 600 mg twice daily and smooth absorption across the day. Pick by goals and dosing convenience: once-daily simplicity here, twice-daily steady levels there.
Should I take it with food or on an empty stomach?
Empty stomach improves absorption. If that bothers your stomach, a small snack works. Either way, separate by at least two hours from mineral supplements and from any thyroid hormone you take, per the warnings below.
How long until I notice anything?
Plan on six to twelve weeks of consistent use before judging the response. Antioxidant effects build with time rather than showing up acutely.
Why is biotin in this formula?
High-dose alpha-lipoic acid competes with biotin at transporters, which can deplete biotin-dependent enzymes over time. The 300 mcg biotin in this product offsets that competition without affecting most lab assays.
Does the biotin in this affect lab tests?
High-dose biotin can interfere with some immunoassays. The 300 mcg here is in the standard supplement range; if your clinician has flagged a test as biotin-sensitive, pause the supplement briefly before the draw.
How to take it & ingredients
Suggested use: 1 capsule per day or as recommended by your health care professional.
Active ingredients
1 capsule per serving · 60 servings
Alpha Lipoic Acid (ALA)
As R-Lipoic Acid
As R-Lipoic Acid
300 mg
Biotin
300 mcg
Sodium
35 mg
Other ingredients: Hypromellose (Natural Vegetable Capsule), Microcrystalline Cellulose, Magnesium Stearate
Certifications
Benefits
Warnings
