Liquid Vitamin D3 with K2 by Ortho Molecular Products

If your Vitamin D, 25-Hydroxy is in the lower part of the normal range and you want a simple maintenance plan, vitamin D3 with K2 drops are a clean fit. They suit adults with little sun, darker skin, consistent sunscreen use, or northern latitude winters. The 1,000 IU D3 here is maintenance-level; if your level is meaningfully low or you have higher body weight, you’ll likely need a larger repletion dose short‑term, then step down. Vegans, dairy-avoiders, and post-menopausal women often find the K2 addon useful for bone strategy.

Cholecalciferol (vitamin D3) is the form your skin makes from sunlight. Your liver and kidneys convert it to the active hormone that raises calcium absorption and helps keep parathyroid hormone (PTH, the signal that pulls calcium from bone) in check. Vitamin K2 as MK-7 activates osteocalcin (a bone-building protein that locks calcium into bone) and matrix Gla-protein, or MGP (a protein that helps keep calcium out of artery walls). Evidence for artery calcification protection is promising but mixed; for bones, D3 plus K2 is a rational pair when calcium intake is adequate.

One drop daily delivers 1,000 IU D3 plus 10 mcg K2 (MK-7). Take it with a meal that contains fat for best absorption, directly on the tongue or mixed in a beverage. Re-test Vitamin D, 25-Hydroxy after 8–12 weeks to confirm you’re on target. Most K2 MK-7 trials use 90–180 mcg per day, so the K2 here is a light, maintenance add-on rather than a high-dose K2 strategy.

Skip K2 if you take warfarin (Coumadin), since vitamin K interferes with how that drug thins blood. Direct oral anticoagulants like apixaban or rivaroxaban are not affected the same way, but ask your clinician. If you have a history of high calcium, recurrent kidney stones, sarcoidosis, or hyperparathyroidism, use D3 only with medical guidance. Thiazide diuretics can raise calcium; combining with high-dose D3 needs monitoring. In pregnancy, maintenance D3 is routine, but clear K2 use with your OB.