Ortho Biotic® Powder by Ortho Molecular Products

If you’re starting or finishing an antibiotic, a probiotic after antibiotics is one of the few evidence-backed moves to keep stools normal. This powder combines 20 billion CFU of lacto-bifido bacteria with 3 billion CFU of Saccharomyces boulardii (a probiotic yeast that antibiotics don’t kill). That pairing fits adults prone to loose stools from antibiotics, frequent travelers, or those with diet or stress-related irregularity who prefer a mixable powder over capsules.

The lactobacillus and bifidobacterium strains crowd out gas-producing microbes, help reinforce the gut lining, and make short-chain fatty acids that steady stool form. Saccharomyces boulardii uniquely survives antibiotics and binds toxins from problem bugs, which is why it cuts antibiotic-associated diarrhea risk in many trials and shortens duration when it happens. Together, these organisms often calm urgency and normalize stool frequency within 2 to 7 days in responders.

Mix one scoop in cool water or a non-hot beverage once daily. Take with a meal to buffer stomach acid. If you’re on antibiotics, take this at a different time of day, at least 2 to 3 hours apart; keep Saccharomyces boulardii going through the full course and for 1 to 2 weeks after. If you’re sensitive, start with a half scoop for 3 to 4 days, then increase. Avoid hot liquids, which can inactivate the cultures.

Skip probiotics with Saccharomyces boulardii if you are severely immunocompromised, are in the ICU, or have a central venous catheter, due to rare bloodstream yeast infections reported in these settings. Do not use alongside antifungal drugs, which will inactivate the yeast. If you have new blood in stool, high fever, or severe abdominal pain, stop and seek medical care rather than self-managing with a probiotic.