Reacted Magnesium 235 mg by Ortho Molecular Products

If you get muscle tightness at night, restless sleep, or frequent tension headaches, magnesium glycinate is a practical first step. This blend pairs glycinate with citrate and malate, so you get gentle absorption plus a mild bowel-regularity effect. It fits adults whose Magnesium, RBC (magnesium inside red blood cells, a better gauge than serum) is low or low-normal, people with high coffee or alcohol intake, and those on proton pump inhibitors who often run low. For constipation-dominant folks, citrate in the mix helps; for daytime energy, malate can be useful.

Magnesium sits at the relaxation side of the nerve–muscle balance, opposing calcium’s contract signal. Adequate levels calm overactive nerve firing, which is why cramps and tension often ease. Glycinate (magnesium bound to the amino acid glycine) is well absorbed and easy on the stomach; citrate draws water into the bowel, explaining looser stools in higher doses; malate feeds the cell’s energy cycle. Together they support sleep quality, regularity, and modest blood pressure reductions in responders over 8 to 12 weeks.

The suggested use is two or more capsules daily. Most adults land between 200 and 400 mg elemental magnesium per day, often split morning and evening to improve absorption and reduce GI upset. Take with a small snack if you’re sensitive. For sleep or nighttime leg cramps, put the larger portion in the evening. Constipation typically improves within 24 to 48 hours, while muscle tension and sleep usually respond within 1 to 2 weeks.

Separate magnesium by at least 2 hours from levothyroxine, antibiotics in the tetracycline or quinolone families, and oral bisphosphonates, since it binds these drugs and blocks absorption. Loop and thiazide diuretics can lower magnesium; potassium-sparing diuretics can raise it. Significant kidney disease raises the risk of magnesium build-up, so use only with clinician guidance. Recheck Magnesium, RBC after 4 to 8 weeks to judge if your dose is adequate.