Instalab
Pure Encapsulations

O.N.E. Multivitamin by Pure Encapsulations

60 capsules · 60-day supply
Once-Daily Multivitamin with Active Folate, CoQ10, and Lutein
$XX.XX$48.50retail
20% below MSRP3rd-party tested for purity & potencyFree shipping $50+
VegetarianGluten Free

Pure Encapsulations O.N.E. Multivitamin overview

This once-daily multivitamin suits adults who want broad micronutrient coverage in a single capsule. It is hypoallergenic, gluten-free, non-GMO, and iron-free, so adults who get iron from food or who supplement iron separately can take it without overlap. The formulation favors active nutrient forms (L-5-MTHF, methylcobalamin, pyridoxal 5'-phosphate, riboflavin 5'-phosphate) and uses well-absorbed mineral chelates.

Each capsule delivers 2,000 IU of vitamin D3 (cholecalciferol), 400 mcg of L-5-MTHF (Metafolin), 500 mcg of methylcobalamin, 25 mg of zinc citrate, and 70 mcg of selenium as selenomethionine. The formula also includes 50 mg of CoQ10 with the sustained-release MicroActive cyclodextrin complex, 50 mg of alpha-lipoic acid, and a carotenoid blend with 3 mg of FloraGLO lutein plus zeaxanthin and lycopene. Together these nutrients support cellular energy, antioxidant defenses, vision, and cognitive function.

Take one capsule daily with a meal that contains some fat, since vitamins A, D, E, K, and the carotenoids absorb better with dietary fat. Morning or midday tends to fit most routines because B vitamins can feel energizing. If you supplement iron, take it at a different time of day, since zinc and iron compete for absorption.

If you take prescription medications, are pregnant or breastfeeding, or are managing a health condition with a clinician, talk to your care team before starting and review the warnings below.

Frequently asked questions

Is this multivitamin iron-free?

Yes, it contains no iron. Adults who get iron from food or who supplement iron separately can take it without overlap.

What makes the folate active?

It uses 400 mcg of L-5-MTHF (Metafolin), the active form of folate the body uses in methylation, rather than folic acid.

How long until I notice an effect from a multivitamin?

Subjective changes vary. Some adults notice steadier daily energy within 1 to 3 weeks, especially when dietary intake of B vitamins was light. Take with food for better absorption of fat-soluble vitamins and carotenoids.

Can I take this multivitamin at night?

You can, although many adults prefer morning or midday because B vitamins can feel energizing. Take it with food in either case for better absorption of fat-soluble vitamins and carotenoids.

Why is the CoQ10 listed as sustained-release?

The CoQ10 is delivered in a MicroActive cyclodextrin complex, a sustained-release format that releases CoQ10 gradually for steadier absorption over the day.

Could the zinc in this multivitamin affect copper status?

Long-term zinc intake at 25 mg per day without added copper can lower copper status in some adults. If you use this long term, consider checking copper status with your clinician.

How to take it & ingredients

Suggested use: Take 1 capsule daily with a meal.
Active ingredients
1 capsule per serving · 60 servings
Vitamin A
Vitamin A acetate, beta-carotene
2381.45 IU, 1125 mcg
Vitamin C
Ascorbic acid
180 mg
Vitamin D3
Cholecalciferol
2000 IU, 50 mcg
Vitamin E
As d-alpha tocopheryl succinate
18 IU, 20 mg
Thiamine
Thiamine HCl (vitamin B1)
3 mg
Riboflavin
Vitamin B2, riboflavin 5'-phosphate (activated B2)
3 mg
Niacin
Niacinamide
20 mg
Vitamin B6
Pyridoxine HCl, pyridoxal 5'-phosphate (activated B6)
4 mg
Folate
Metafolin (L-5-MTHF)
667 mcg DFE, 400 mcg
Vitamin B12
Methylcobalamin
500 mcg
Biotin
300 mcg
Pantothenic acid
Calcium pantothenate (vitamin B5)
10 mg
Iodine
Potassium iodide
150 mcg
Zinc
Zinc citrate
25 mg
Selenium
Selenium as selenomethionine
70 mcg
Manganese
Manganese citrate
2 mg
Chromium
Chromium polynicotinate
200 mcg
Molybdenum
TRAACS molybdenum glycinate chelate
75 mcg
Boron
Boron glycinate
1 mg
Choline
Choline bitartrate
25 mg
Inositol
25 mg
Coenzyme Q10 (sustained-release)
CoQ10, MicroActive CoQ10-cyclodextrin complex
50 mg
Alpha-lipoic acid
50 mg
Lutein
FloraGLO lutein
3 mg
Zeaxanthin
OPTISHARP brand
0.5 mg
Lycopene
Tomat-O-Red natural tomato extract
0.5 mg
Other ingredients: Vegetarian capsule (cellulose, water), Potato starch, Ascorbyl palmitate