Vitamin D + K2 Liquid by Thorne

If you’re looking for a maintenance-level vitamin D3 K2, this liquid fits adults whose Vitamin D, 25-Hydroxy is in the lower part of the normal range and who want a gentle daily dose. It’s practical if you get little sun, have darker skin, use sunscreen, live at northern latitudes, or dislike pills. The 1,000 IU vitamin D3 per serving is upkeep, not repletion—if your level is meaningfully low, you’ll usually need a higher dose short term, then step down. Vegans and dairy-avoiders also benefit from the added K2.

Vitamin D3 raises calcium absorption from the gut and tones down parathyroid hormone (the signal that pulls calcium from bone). Vitamin K2 activates proteins like osteocalcin (which helps lock calcium into bone) and matrix Gla protein (which keeps calcium out of soft tissues like arteries). This formula uses MK-4, the K2 form found in animal foods and human tissues; it’s fast-acting compared with MK-7, and both forms activate the same proteins. Claims about big immune effects are modest at best—think bone and calcium balance first.

Take 2 drops one to three times daily with a meal that contains some fat for better absorption. You can add the liquid to food or a drink. Keep the daily pattern steady and retest Vitamin D, 25-Hydroxy after 8 to 12 weeks to judge your personal dose. If your level remains low, increase under clinician guidance. Calcium can be taken alongside. This vitamin D3 K2 doesn’t need refrigeration; store at room temperature.

Skip K2 if you take warfarin or other vitamin K–antagonist blood thinners; added K2 changes their effect and requires prescriber-managed dosing. Newer anticoagulants that don’t target vitamin K are different, but still clear supplements with your clinician. Use medical supervision if you’ve had high calcium, recurrent kidney stones, sarcoidosis, or primary hyperparathyroidism, and monitor Calcium and PTH. Orlistat or bile acid sequestrants (cholestyramine, colesevelam) reduce absorption—separate dosing by several hours.