Motility PRO by Ortho Molecular Products

If you bloat easily or feel overly full long after meals, a gentle prokinetic supplement can help move things along between meals. This artichoke leaf extract plus ginger is a fit for people with slow migrating motor complex (the fasting clean‑up waves that sweep the small intestine) and for those managing small intestinal bacterial overgrowth after treatment who want relapse prevention. It’s also reasonable for dyspepsia (upper‑abdominal discomfort) when your labs are otherwise unremarkable. If you’re severely constipated or have significant reflux, this light dose is often too mild as a stand‑alone.

Artichoke leaf extract increases bile flow from the liver and gallbladder, which can nudge intestinal movement and improve fat digestion that otherwise slows the system. Ginger stimulates stomach and small‑bowel contractions, speeding gastric emptying and reducing nausea. Together they encourage the migrating motor complex (those between‑meal waves) to clear residual food and bacteria toward the colon. In practice, patients notice less post‑meal fullness and gas, and some see steadier bowel rhythm. Evidence is modest, but consistent with clinical use over decades.

Take 1 capsule daily on an empty stomach, ideally 60–90 minutes after dinner or first thing on waking, so it lands during a fasting window when the migrating motor complex is active. If you’re coming off antibiotics or herbal antimicrobials for small intestinal bacterial overgrowth, many clinicians continue a prokinetic for 6–12 weeks. Expect gut‑feel changes within 7–14 days; give it a full month before judging. If heartburn occurs, move the dose farther from bedtime.

Skip if you have known bile duct obstruction or symptomatic gallstones; artichoke can increase bile flow and provoke pain. Use caution with significant gastroesophageal reflux, as ginger can aggravate heartburn. Ginger can interact with blood thinners (warfarin, apixaban, clopidogrel) by increasing bleeding risk. Allergy to ragweed family (Asteraceae) is a reason to avoid artichoke. Pregnancy or breastfeeding: talk with your clinician rather than self‑starting, given limited data at this low dose.