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This formula blends four forms: calcium citrate, dicalcium malate, calcium bisglycinate (a chelated form bound to the amino acid glycine for easier uptake), and microcrystalline hydroxyapatite (the calcium‑phosphorus mineral your bones are made of). Multiple forms improve absorption even with reduced stomach acid. Calcium, with vitamin D3, lowers parathyroid hormone (the signal that pulls calcium from bone), helping you maintain bone over time. Expect changes on bone markers and scans over months, not weeks.
Per label, take 1–2 capsules three times daily, ideally with meals. The critical rule is dose size: the gut absorbs calcium best in divided amounts around 500–600 mg elemental at a time. This product provides 500 mg per serving, so spread intake across the day. Separate calcium by 2–4 hours from iron, levothyroxine, tetracyclines or fluoroquinolone antibiotics, and bisphosphonates. If you use a proton‑pump inhibitor, citrate and bisglycinate remain well absorbed with meals.
Skip supplementation and speak with your clinician if you have a history of high blood calcium, recurrent kidney stones, sarcoidosis, primary hyperparathyroidism, or advanced kidney disease. Thiazide diuretics can raise calcium levels; monitor if you use them. For stone‑formers who still need calcium, take it with meals and discuss a 24‑hour urine calcium test. Constipation is the most common side effect; increase fluids, fiber, and magnesium if needed.
Count food first, then supplement only the gap. Most adults need roughly 1,000–1,200 mg total intake daily from diet plus supplements. Avoid taking more than about 500–600 mg elemental at one time because absorption drops with larger single doses.
Citrate is absorbed well even with low stomach acid and tends to be gentler on the gut. This blend also includes bisglycinate, dicalcium malate, and hydroxyapatite to cover different uptake routes. Carbonate requires more stomach acid and can cause more gas for some people.
Yes, vitamin D makes calcium usable. This formula includes 10 mcg (400 IU) of vitamin D3, which is a maintenance amount. If your Vitamin D, 25-Hydroxy is low, you will likely need a higher D3 dose temporarily under clinician guidance, then step down.
Bone changes slowly. Expect months to a year to see effects on a DXA scan. Consistent calcium, adequate vitamin D, protein intake, and resistance training are the levers that move bone the most. Short trials rarely show meaningful changes.
Dietary calcium with meals generally lowers oxalate absorption and can reduce certain stone risks. High-dose calcium supplements between meals can raise risk in susceptible people. If you have a stone history, take calcium with food and ask about a 24‑hour urine evaluation.
Data are mixed. Large food‑first calcium intake looks neutral, while some studies raised concern with high-dose supplements. A practical approach is to meet most needs from diet, then use divided, meal‑time doses to fill gaps rather than large boluses.
Yes. Calcium citrate and bisglycinate are absorbed even with low stomach acid. Take with meals and split doses across the day. Avoid carbonate if you have persistent low acid, as it depends more on stomach acid for absorption.
Calcium binds many drugs and minerals. Separate by 2–4 hours from iron, levothyroxine, tetracycline or fluoroquinolone antibiotics, and bisphosphonates. Thiazide diuretics can raise blood calcium; monitor with your clinician if you use them.



