SBI Protect® Capsules 2.42 g by Ortho Molecular Products

If loose stools or urgency linger after a gut infection, bovine immunoglobulin can be a practical, non-absorbed option to steady things. It’s a fit for post-infectious IBS patterns, athletes with “runner’s gut,” frequent travelers, and those with stool tests showing elevated fecal calprotectin (a marker of gut inflammation) or low secretory IgA (the gut’s antibody output). If you’re dealing with elevated hs-CRP (a whole‑body inflammation marker), improvements tend to be modest and follow gut symptom gains.

These immunoglobulins act like sponges in the intestinal lumen, binding bacterial fragments such as LPS (lipopolysaccharide, a cell wall trigger for inflammation), flagellin, and other antigens. Bound targets are carried out in stool instead of activating the immune system. With fewer irritants hitting the lining, tight junctions (the proteins that seal cells together) function better, which often shows up as firmer stools and less post-meal bloating. Unlike human IVIG, this stays in the gut and is not absorbed systemically.

Ortho Molecular’s capsule provides 2.42 g ImmunoLin per day at the suggested 4-capsule dose, which matches typical clinical use. Take with or without food; many patients do best splitting the dose morning and evening. Separate by at least 2 hours from oral medications or iron, as immunoglobulins can bind compounds in the gut. Expect stool consistency to improve within 2 to 4 weeks, with broader symptom changes over 4 to 8 weeks. You can pair it with a probiotic or butyrate without issue.

Avoid if you have a beef allergy or alpha-gal syndrome (the tick-related red meat allergy). Milk allergy is usually not a problem because this is serum-derived, not a milk protein, but discuss with your clinician if your reactions are severe. This is not a substitute for treating active infections, celiac disease dietary gluten removal, or inflammatory bowel disease care. Pregnancy and breastfeeding: data are limited; use only with clinician guidance.