Instalab
Pure Encapsulations

Saw Palmetto 320 by Pure Encapsulations

120 softgels · 120-day supply
Support for Prostate Health and Hormonal Balance
$89.50retail
Add to cart for 20% off
20% below MSRP3rd-party tested for purity & potencyFree shipping $50+

Pure Encapsulations Saw Palmetto 320 overview

Men with mild urinary symptoms from an enlarged prostate, like frequent nighttime trips and a weak stream, are the best fit for saw palmetto 320 mg. It’s reasonable if you want a plant-based option before or alongside lifestyle changes. If you have fever, burning with urination, blood in urine, or very slow flow, see a clinician first. Tell your provider if you’re taking this before a PSA (Prostate-Specific Antigen) test.

Saw palmetto extract is rich in fatty acids that partially inhibit 5‑alpha‑reductase, the enzyme that turns testosterone into dihydrotestosterone (DHT, the more potent form that drives prostate growth). It also appears to block DHT binding on prostate cells and modestly calm inflammatory signaling. In practice, responses vary: older meta-analyses suggested small symptom improvements, while newer, higher‑quality trials show little to no average benefit. Individual trial runs are the fairest test.

The extract here provides 320 mg standardized to 85% fatty acids, the dose most commonly studied. The label suggests 1–2 capsules per day, divided, between meals. Many people tolerate it better with a small snack, and fat in food may aid absorption. Give it 4 to 8 weeks to judge changes in nighttime urination and flow. If nothing shifts by 12 weeks, it’s unlikely to help you.

Skip or clear this with your clinician if you use blood thinners or antiplatelet drugs, as bleeding risk can rise. Tell your doctor if you also take finasteride or dutasteride, since effects can overlap and PSA results can be harder to interpret. Stop 1–2 weeks before surgery. Pregnancy and breastfeeding: avoid. Severe urinary retention, recurrent infections, or suspected prostate cancer warrant medical evaluation, not a supplement trial.

Frequently asked questions

Does saw palmetto actually work for an enlarged prostate?

It helps some men with mild lower urinary tract symptoms, but results are inconsistent. Large modern trials show little average benefit. A 6–12 week trial is reasonable; if you notice no change, stop and consider other options with your clinician.

How long does saw palmetto take to work?

Give it 4 to 8 weeks to gauge changes in nighttime urination and stream strength. If there’s no meaningful improvement by 12 weeks, it’s unlikely to help you and you should reassess the plan.

Does saw palmetto affect PSA test results?

It can modestly influence PSA (Prostate-Specific Antigen) readings in some users. Always tell your clinician and the lab that you’re taking saw palmetto before PSA testing so they can interpret results appropriately.

Can I take saw palmetto with finasteride or tamsulosin?

With finasteride or dutasteride, overlap in mechanism can complicate PSA monitoring; ask your prescriber. With tamsulosin (an alpha‑blocker), some clinicians allow combination, but monitor symptoms and side effects closely.

What are the common side effects of saw palmetto?

Most people tolerate it well. The most common effects are mild stomach upset, nausea, or headache. Taking it with a light snack can help. Stop and seek care for unusual bleeding, severe pain, or allergic symptoms.

Does saw palmetto lower testosterone or cause sexual side effects?

Clinically meaningful drops in testosterone are uncommon. Some users report sexual side effects, but rates are low and less consistent than with prescription 5‑alpha‑reductase inhibitors. If you notice issues, discontinue and discuss alternatives.

Is saw palmetto safe for women?

It’s generally not recommended in pregnancy or breastfeeding, and women with hormone‑sensitive conditions should avoid it unless a clinician advises otherwise. For nonpregnant women, discuss risks and benefits with your provider.

Should I take saw palmetto with food or on an empty stomach?

The label suggests between meals, but many people tolerate it better with a small snack, and dietary fat may aid absorption. Choose the approach you tolerate best and stay consistent day to day.

How to take it & ingredients

Suggested use: Take 1–2 capsules per day, in divided doses, between meals.
Active ingredients
1 softgel per serving · 120 servings
Saw Palmetto Extract
Serenoa repens, fruit, standardized to contain 85% total fatty acids and 0.15% phytosterols
320 mg
Other ingredients: Gelatin capsule (gelatin, glycerin, water)