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Thorne

Zinc Picolinate 15mg by Thorne

60 capsules · 60-day supply
Essential Zinc for Immune Function and Cellular Health
$XX.XX$15.00retail
20% below MSRP3rd-party tested for purity & potencyFree shipping $50+
Gluten FreeSoy FreeDairy FreeMilk Free

Thorne Zinc Picolinate 15mg overview

This is a fit if you want a gentle, well-absorbed zinc picolinate 15 mg for maintenance rather than aggressive repletion. It’s useful when Zinc, Plasma or Serum is low or low-normal, if you rarely eat shellfish or red meat, follow a high‑phytate diet (lots of grains/legumes), are vegan, or have gut issues like celiac, inflammatory bowel disease, or post-bariatric surgery. Athletes with heavy sweat loss and those with frequent colds, poor wound healing, or reduced taste/smell also tend to benefit.

Zinc picolinate binds zinc to picolinic acid, which improves absorption compared to harder-to-absorb forms like zinc oxide. Once absorbed, zinc is a cofactor for hundreds of enzymes involved in DNA repair and cell division, which is why skin, nails, and wound healing respond. It also supports the activity of copper-zinc superoxide dismutase (an enzyme that neutralizes damaging free radicals) and helps immune cells mature and signal effectively. For colds, the evidence is specific to high-dose zinc lozenges started early; capsules aren’t the same intervention.

Take 1 capsule once or twice daily as directed. Zinc can cause mild nausea on an empty stomach, so take with food if that happens. Separate from iron or calcium supplements by at least 2 hours, since they compete for absorption. If your Zinc, Plasma or Serum is meaningfully low, short-term higher dosing is sometimes used under clinician guidance, then stepped down to 15 mg for upkeep.

Zinc binds certain medications in the gut and blocks their absorption. Separate by at least 4 hours from antibiotics in the tetracycline or quinolone families, and from levothyroxine (thyroid hormone). Long-term higher zinc can lower copper, so if you take zinc daily for months, consider checking Copper, Serum. If you’re managing Wilson’s disease or on chelators, coordinate supplementation with your specialist.

Frequently asked questions

Is 15 mg of zinc picolinate enough?

For maintenance, 15 mg is a reasonable daily dose. If you have established deficiency on Zinc, Plasma/Serum or clear signs like poor wound healing, clinicians often use higher short-term doses, then step down. Recheck labs after 8–12 weeks.

Should I take zinc picolinate with food or on an empty stomach?

Either is fine, but zinc can cause nausea on an empty stomach. If you feel queasy, take it with a meal. Avoid taking it alongside iron or calcium; separate by at least 2 hours to protect absorption.

How long does zinc picolinate take to work?

Immune and energy effects are gradual; skin, nail, and taste changes typically improve within 4–8 weeks if low zinc was the driver. Plan to recheck Zinc, Plasma/Serum in 8–12 weeks to confirm the dose is working.

Does zinc picolinate help with colds?

Only specific high-dose zinc lozenges taken at the first symptoms consistently shorten colds. Daily zinc capsules are for maintaining status, not for acute cold treatment.

Can zinc picolinate cause copper deficiency?

At higher intakes for long periods, zinc can lower copper absorption. If you supplement daily for months, especially above 15–30 mg, consider checking Copper, Serum and discuss duration with your clinician.

What drugs should not be taken with zinc?

Separate zinc from tetracycline or quinolone antibiotics and from levothyroxine by at least 4 hours. Also separate from iron and calcium supplements by 2 hours to avoid competition for absorption.

Is zinc picolinate better than zinc gluconate or oxide?

Picolinate is well absorbed and generally outperforms oxide. Gluconate and citrate are also well absorbed. Tolerance and cost matter more than tiny absorption differences for most people at maintenance doses.

Is zinc picolinate safe during pregnancy?

Zinc is essential in pregnancy, but total intake should be coordinated with your prenatal. If you’re already on a prenatal, ask your clinician before adding extra zinc to avoid unnecessary stacking.

How to take it & ingredients

Suggested use: Take 1 capsule one to two times daily or as recommended by your health professional.
Active ingredients
1 capsule per serving · 60 servings
Zinc
Picolinate
15 mg
Other ingredients: Hypromellose Capsule, Leucine, Microcrystalline Cellulose, Silicon Dioxide