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Citrate is magnesium bound to citric acid. It dissolves easily and is absorbed better than magnesium oxide. Absorbed magnesium is a cofactor for hundreds of enzymes, including the ones that make cellular energy; it helps muscles relax after they contract, supports normal nerve signaling and heart rhythm, and is part of bone mineral. The portion that is not absorbed holds water in the intestine, which softens stool and explains this form's mild laxative effect.
The label directs 2 capsules daily, which provide 300 mg of magnesium, or 150 mg per capsule. Take it with food, and split it between two meals if your stomach or bowels are sensitive. Starting with 1 capsule for a few days before moving to 2 is a sensible way to find your tolerance. Evening suits people who take it to wind down. If you are correcting a low level, recheck Magnesium or RBC Magnesium after 4 to 8 weeks.
Magnesium binds several medicines in the gut. Take it at least 2 hours apart from tetracycline and quinolone antibiotics and from bisphosphonates, and 4 hours from levothyroxine. People with kidney disease clear magnesium poorly and should not supplement without their clinician's supervision. Loose stools or cramping mean the dose is more than your gut tolerates, so cut back or split it. If you are pregnant, nursing or on prescription medicines, check with your clinician first.
Softer, easier stools usually show within a day or two. Muscle tightness and sleep take 1 to 2 weeks, and lab values 4 to 8 weeks. Compared with glycinate, citrate helps the bowels but is more likely to loosen them; compared with oxide, more of it is absorbed. This is a supplement dose, not the liquid magnesium citrate used for bowel preparation, and ongoing constipation is something to raise with your clinician.
It is a well-absorbed form used to bring a low magnesium level up and to support muscle function, relaxation and bone health. It also holds water in the bowel, so it is the form most often chosen by people who want help with regularity as well.
The label gives 300 mg of magnesium, as magnesium citrate, per 2-capsule serving, which is 150 mg per capsule. That figure is the magnesium itself, not the weight of the magnesium citrate compound.
It can. Citrate draws water into the bowel, and a 300 mg serving loosens stools for some people. Start with 1 capsule, take it with food, and split the serving across two meals. If stools stay loose, lower the dose or switch to magnesium glycinate.
The label directs 2 capsules daily. Take them with a meal, at whatever time you will remember; evening suits people taking it for relaxation or sleep. Splitting the 2 capsules between two meals is easier on the gut and may improve absorption.
Both are well absorbed. Citrate helps with regularity and is more likely to loosen stools. Glycinate is gentler on the gut and is the usual choice when sleep or relaxation is the goal and bowels are already regular or loose.
Separate them. Magnesium binds levothyroxine, tetracycline and quinolone antibiotics, and bisphosphonates in the gut. Take magnesium at least 2 hours from the antibiotics and bisphosphonates and 4 hours from levothyroxine, and confirm timing with your pharmacist.
Only under a clinician's supervision. The kidneys remove excess magnesium, and when they are impaired magnesium can build up to unsafe levels. If you have chronic kidney disease, get your clinician's agreement and lab monitoring before supplementing.
Expect 4 to 8 weeks of steady daily use before Magnesium or RBC Magnesium reflects the change. Retest at about two months. Cramps or sleep may improve sooner, within 1 to 2 weeks, if low intake was the cause.



