Cortisol Manager by Integrative Therapeutics

If you want a calm wind-down without melatonin and you tolerate the soy-derived phosphatidylserine source, this is the original tablet form of Cortisol Manager in a three-month supply. It suits adults committing to a sustained nightly routine: people working through a longer-stretch project, parents in a high-stakes season, anyone whose evenings feel mentally busy and want to settle into a consistent pre-sleep pattern. Per Integrative Therapeutics, the formula supports balanced cortisol and a healthy stress response.

The stress-reducing blend pairs Sensoril ashwagandha with L-theanine. Sensoril is a standardized ashwagandha extract; per Integrative Therapeutics, a 2008 placebo-controlled trial showed it significantly reduced serum cortisol versus placebo. L-theanine, an amino acid from green tea, supports a relaxed-alert state. The cortisol-reducing blend pairs magnolia bark extract (standardized to 2% honokiol and 1% magnolol) with epimedium aerial-parts extract. Phosphatidylserine, sourced here from soybean lecithin, contributes to the membrane signaling involved in the body's stress-response system.

Per Integrative Therapeutics: adults take 1 tablet before bedtime, or as recommended by a healthcare professional. Increase to 2 tablets during periods of high stress. For nightly use. At one tablet per night, the 90-tablet bottle lasts roughly three months, which is enough time to give ashwagandha its 2-to-8-week ramp and judge sustained effects on stress patterns.

If you take prescription medications, are pregnant or breastfeeding, or are receiving cancer treatment, talk to your clinician before starting and review the warnings below.