DG Protect 350 mg by Ortho Molecular Products

This fits people who eat mostly gluten-free and dairy-light but still get bloating, gas, or loose stools from accidental exposure at restaurants or travel. It’s for lactose intolerance or non-celiac gluten sensitivity, not for diagnosed celiac disease. If your tTG-IgA (tissue transglutaminase IgA, the standard celiac screen) is positive, strict avoidance remains the treatment. It’s also useful if a lactose breath test confirmed lactose malabsorption and you want coverage when you can’t control ingredients.

The blend pairs lactase (the enzyme that breaks down milk sugar) with targeted proteases that cut the hard‑to-digest gluten and dairy proteins. Endopeptidases slice long gluten strands, and exopeptidases trim the leftover peptide ends, reducing the gas and pressure many feel after cross-contact meals. These enzymes can lower the load of troublesome gluten fragments and casein peptides, but they don’t fully neutralize the immune-triggering pieces in celiac disease, so they are an add-on for slipups, not a license to eat freely.

Take one capsule right before the first bite, or within the first few minutes of eating. That timing puts the enzymes in the same place and time as the gluten, lactose, and casein from the meal. Effects are meal-specific, not cumulative; you should notice the difference with that meal. For very large or protein-heavy meals, some clinicians allow a second capsule, but start with one and assess. No special co-factors are needed, and it can be used with most probiotics or fiber.

Skip this if you have celiac disease, wheat allergy, or a true milk protein allergy; use strict avoidance and medical guidance instead. Ongoing abdominal pain, weight loss, anemia, or elevated fecal calprotectin (a stool marker of gut inflammation) needs evaluation, not an enzyme. If you have active ulcers, pancreatitis, or take blood thinners and bruise easily, check with your clinician first. Pregnancy and pediatric use should be guided by a healthcare professional due to limited data.