Resvoxitrol by Ortho Molecular Products

If your hs-CRP (a blood marker of inflammation) runs high or you’re focused on healthy aging, an Nrf2 supplement is a practical way to push your own antioxidant systems harder. This blend fits adults who don’t eat much broccoli-family vegetables, have metabolic stress from extra weight or sedentary time, or want joint comfort beyond fish oil. If you’re already on turmeric and still inflamed, adding glucoraphanin (the sulforaphane precursor) and resveratrol gives a different lever to pull.

Glucoraphanin from broccoli seed converts to sulforaphane, which flips on Nrf2 (the switch that turns on your cells’ own antioxidant-making genes, like glutathione enzymes). Curcumin from a complete turmeric matrix, resveratrol, and andrographolides also signal Nrf2 while dialing down NF-κB (a pro‑inflammatory master switch). Clinically, that combo is why some people see modest drops in hs-CRP within 4 to 12 weeks and better tolerance of exercise or joint load.

Take 2 capsules daily with a meal that contains some fat; curcumin and resveratrol absorb better with food. For extra sulforaphane yield, take it alongside a bite of mustard, daikon, or other myrosinase-containing food, which helps convert glucoraphanin. Expect any inflammation changes on labs like hs-CRP after 4–12 weeks. If you track lipids or fasting insulin, recheck on the same timeline to see broader metabolic effects.

Use caution with anticoagulants or antiplatelet drugs, since turmeric and resveratrol can increase bleeding tendency. Andrographis can interact with immunosuppressants and may slightly lower blood pressure or blood sugar; monitor if you use antihypertensives or diabetes meds. Avoid in pregnancy or while trying to conceive, and skip if you have active bile duct obstruction or painful gallstones. If you have liver disease, check AST/ALT after a few weeks.